BioMed Research International
Volume 2016 (2016), Article ID 4524862, 10 pages
http://dx.doi.org/10.1155/2016/4524862

Research Article

Differences in Knowledge, Attitude, and Behavior towards HIV/AIDS and Sexually Transmitted Infections between Sexually Active Foreign and Chinese Medical Students

Martin Kuete,1,2 Qiao Huang,³ Abid Rashid,⁴ Xiu Lan Ma,¹ HongFang Yuan,¹ Juan Pablo Escalera Antezana,⁵ Rakhmanov Yeltay,⁶ Meng Rao,¹ Qian He,⁷ ChengLiang Xiong,¹ and HuiPing Zhang¹

¹Family Planning and Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China
²Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, P.O. Box 3011, Messa, Yaoundé, Cameroon
³School of Nursing, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China
⁴Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China
⁵Department of Trauma Surgery, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China
⁶Department of Orthopaedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China
⁷Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China

Received 3 January 2016; Accepted 25 March 2016

Academic Editor: Lucia Lopalco

Copyright © 2016 Martin Kuete et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract.

Although the prevalence of human immunodeficiency virus (HIV) decreased in the last decade worldwide, the number of deaths due to HIV/AIDS and communicable diseases including syphilis, hepatitis, and tuberculosis had dramatically increased in developing countries. Education and behavior are incredibly important factors to prevent these diseases’ spread. This study highlights the range of differences in knowledge, attitude, and behavior of 434 sexually active medical students towards HIV/AIDS and sexually transmitted infections (STIs). Because the surveyed population constitutes the forefront of healthcare providers and was originated from different area of the world, this is the first time a study sought to investigate the behavioral attitude of this group of population irrespective of the three levels of their academic and professional knowledge. Several factors including sociodemographic characteristics, sexual behavior, HIV/AIDS, and STIs related patterns play a key role in medical student attitude and behavior towards people infected with HIV/AIDS and STIs. Our findings add consistent value in prior studies which aimed to stop new infections and also imply further investigations on the management of the studied infections by medical students. The present study arouses much interest among participants and provides evidence of reinforcing medical students’ education on HIV/AIDS and STIs.

1. Introduction

Despite the great effort made by governments and international organisations to stop new HIV infection and reduce sexually transmitted infections by 2015 [1, 2], evidences show that communicable infections continue to thrive while decimating millions of lives in developing countries [3–7]. These infections are going beyond the most vulnerable population groups worldwide including migrants. Many studies demonstrated that HIV infection is shifting from men who have sex with men (MSM) to heterosexuals especially among youth at reproduction age [8–10]. The current state is more apparent in China where local and overseas migration and economic development are rapidly growing up. Alongside of this, China is the most populous country in the world and may play a key role in efficiently managing epidemics. Recently, because of nonachievement of millennium development goals on HIV/AIDS in different regions in the world especially in developing countries, the Joint United Nations Programme on HIV/AIDS has fixed new objectives to overcome HIV infection by 2030 [11].

Looking at the paradigm to fight against HIV with the aim of providing the treatment to all infected people regardless of their biological and clinical stage [12], several other key objectives such as making antiretroviral therapy (ART) available and accessible to all patients, strengthening healthcare systems, or improving prevention programmes across general populations are also worthy. Additionally, enhancing strategic measures to encourage the overwhelming number of HIV infected unknown individuals to undergo the test, engaging newly infected people into the treatment programme and healthcare providers support, and advancement of testing, treatment, and follow-up of patients are crucial.

In the last decade, China became not only more attractive in business or political affairs but also one of the main international destinations for education, especially in the field of medicine. Many foreign students studying in Chinese universities are from countries with high prevalence of communicable diseases; it is gainful and invaluable to have extensive knowledge in HIV/AIDS and STIs for practical issues when returning back home after graduation. Then, several studies revealed that barriers including lack of adequate knowledge, misconceptions, negative feeling, refusal, or even discrimination were found among healthcare professional in providing medical care and monitoring HIV/AIDS patients [13–19]. Therefore, to end HIV/AIDS epidemics in the further years, medical students are the workforce of health system and should be provided with well training in HIV/AIDS and sexually transmitted diseases to be able to provide holistic care regarding these infections which are predominant in developing world. In this study, we hypothesized that differences existed in knowledge, attitude, and behavior related to HIV/AIDS and sexually transmitted infections among foreign and local medical students trained in China. Therefore, we aimed to explore and analyze the differences existing in knowledge, attitude, and behavior towards HIV/AIDS and STIs among foreign and local medical students in Chinese university.

2. Methods

2.1. Study Design

The authors designed a cross-sectional study using validated self-administered questionnaire. We focused on the rationale of this study to compare and show differences existing between foreigner and Chinese medical students’ knowledge, attitude, and behavior (KAB) towards HIV/STIs infected persons. The survey tool was firstly designed in English for foreign students then translated into Chinese language. Both English and Chinese versions were discussed and pilot-studied before the final usage.

2.2. Setting, Location, and Period of the Study

This study was conducted in Tongji Medical College affiliated to Huazhong University of Science and Technology (HUST) located in Wuhan, the capital city of Hubei province known as the Chinese education city. According to the latest Chinese ranking universities, Tongji Medical College belongs to the top 1% of Chinese medical schools and is the mostly reputed for its numerous medical programs taught in English. The number of foreigners enrolled for a degree programme during the last 5 years has significantly increased to about 1500 international students annually [20, 21]. Participants were recruited during the normal weekends from March 01 to June 14, 2015.

2.3. Participants Study Size and Eligibility

Total of 434 medical students (MBBS/Bachelor, Master, and Doctor) were randomly selected among students regularly registered and living in students’ campus apartments. 157 foreign students enrolled in English medical degree programme and 277 Chinese medical students all sexually active were included in this study (student who had have or are currently engaged with a sexual partner).

2.4. Sources and Methods of Selection of Participants

All students were previously informed of educational based characteristics of the survey through posters announcement and presurvey activities formed to inform and discuss with respondents publicly across the school campus. During this phase, investigators covered approximately 98% of study population. The final step consisted of using “student door-by-door strategy” which consisted of randomly selecting student’s room from all apartments in the campus residency and inviting student to participate. To ensure the confidentiality and increase participation rate, student was asked to drop the anonymous questionnaire filled in a box placed at the entry of apartment. All students enrolled in nondegree programme and nonsexually active were excluded. Participation rate was estimated to be 65% for foreigners and 78% of surveyed local students.

2.5. Questionnaire and Measurement

2.5.1. Participants’ Baseline Characteristics

The following variables were gathered: gender, age, education level, marital status, region of origin, sexual orientation, number of sex partners, frequency of condom use and enjoyment during sexual intercourse, history of HIV and STIs testing, and vaccination for curable infections (syphilis, hepatitis B and hepatitis C, and tuberculosis).

2.5.2. HIV/AIDS Knowledge and Sources of Information

The variables were measured through a series of 7 yes or no questions on HIV/AIDS cause, progression, and prevention; the main sources of information included 8 items while the assessment of HIV risk factors was subdivided into the route of transmission containing right and wrong responses (16 items), high risk individuals (8 items), and risk factor increasing HIV transmission (7 items). In addition, 3 other questions were related to previous extracurricular training in HIV and STIs, student belief of sufficient knowledge about studied infections (HIV/AIDS, syphilis, hepatitis, and tuberculosis), and student willingness to know more about HIV/AIDS.

2.5.3. Attitude and Behavior

Variables describing student attitude and behavior comprised 21 questions mainly on sexual behavior and condom use, HIV and STIs testing, their attitude vis-à-vis friend/classmate infected with HIV, and students’ opinions related to the support of government and NGOs towards HIV/AIDS patients. We also assessed student’s beliefs regarding HIV/AIDS comparing to other STIs and tuberculosis and moreover the relationship between HIV infection and ethnicity and the current development of China.

2.5.4. Discrimination and Support of Medical Students towards HIV/AIDS Individuals

Variables describing the discrimination and support of students towards HIV/AIDS patients derived from 13 items of the questionnaire which included both positively and negatively framed questions.

2.6. Statistical Methods

Data entry was done using Epidata version 3.5 and all analyses were conducted with SPSS version 18.0. In short, we used numbers and percentages to present most of data while () was use for nonnormal continuous variables; the Mann-Whitney test (-value) for continuous variables was conducted to compare measurements between Chinese and foreign students. Categorical variables were compared using (for comparing proportions) tests. Where possible when assessing the knowledge, attitude, and behavior, we assigned 1 for every positive response and 0 for wrong answer. For brevity and clarity, we reported only significant factors influencing discrimination and support in multivariate logistic regression analyses. Odds ratio (OR) with 95% of confident interval (CI) was calculated to fit association levels between students’ characteristics and discrimination or support of HIV/AIDS individuals. All tests were two-tailed and results were considered significant at .

2.7. Ethics Statement

Ethical clearance was previously obtained from the institutional review board of Tongji Medical College of Huazhong University of Science and Technology under authorization number IORG S115. Moreover, all participants provided a written informed consent attached with the questionnaire at the time of the survey.

3. Results

3.1. Students’ Baseline Characteristics

Data summarized in Table 1 showed that no statistical difference existed between these sexually active students regarding their education level and condom use during sexual intercourse. However, many patterns including gender, marital status, sexual orientation, HIV testing, and screening for other infections studied (syphilis, hepatitis B and hepatitis C, and tuberculosis) significantly varied between foreign and Chinese medical students.

Table 1: Participants baseline characteristics.

Variables
Categories
Foreign students ()
Chinese students ()
value

Gender
Male
84 (53.50)
110 (39.71)
0.0055

Female
73 (46.50)
167 (60.29)

Median age (IQR)
—
24 (22–26)
25 (23–29)
0.0042

Education level
Bachelor
66 (42.04)
116 (41.88)
0.982

Master
66 (42.04)
115 (41.52)

Doctor
25 (15.92)
46 (16.61)

Marital status
Married
33 (21.02)
64 (23.10)
<0.001

Single
77 (49.04)
186 (67.15)

Partnered
47 (29.94)
27 (9.75)

Region of origin
Asia
62 (39.49)
—
—

Europe
22 (14.01)
—

Africa
49 (31.21)
—

Others
24 (15.29)
—

Sexual orientation
Heterosexual
143 (91.08)
249 (90.22)
0.006

Homosexual
5 (3.18)
23 (8.33)

Bisexual
9 (5.73)
4 (1.45)

Number of sex partners
1
110 (70.06)
240 (86.64)
<0.001

2
39 (24.84)
34 (12.27)

≥3
8 (5.1)
3 (1.08)

Frequency of condom use during sexual intercourse
Every time
68 (43.31)
135 (48.74)
0.1566

Often
79 (50.32)
115 (41.52)

Never
10 (6.37)
27 (9.75)

Sex enjoyment with condom
Yes
91 (57.96)
198 (71.48)
<0.0001

No
64 (40.76)
32 (11.55)

Do not know
2 (1.27)
47 (16.97)

Latest HIV testing
Never tested
12 (7.64)
217 (78.34)
<0.0001

3 months ago
5 (3.18)
17 (6.14)

6 months ago
25 (15.92)
11 (3.97)

1 year ago
47 (29.94)
13 (4.69)

≥2 years ago
68 (43.31)
19 (6.86)

Previously tested for STIs and tuberculosis
Syphilis
57 (55.41)
87 (20.58)
<0.0001

Hepatitis B
101 (73.29)
203 (64.33)
0.0504

Hepatitis C
93 (59.24)
92 (33.21)
<0.0001

Tuberculosis
91 (57.96)
68 (24.55)
<0.0001

Previous vaccination
Hepatitis B
102 (79.42)
220 (64.97)
0.0009

Tuberculosis
94 (52.23)
82 (33.94)
0.0002

is significant; IQR: interquartile range; HIV: human immunodeficiency virus; STIs: sexually transmitted infections.

3.2. Knowledge and Sources of Information Related to HIV/AIDS

Despite the fact that no difference was found in participants’ education level, this study revealed a huge difference in HIV/AIDS knowledge between Chinese and foreign students (see Table 2). Overall, Chinese students were more knowledgeable compared with their counterparts in many factors. For instance, only 49.68% of foreign students compared to 95.67% of Chinese provided the right answer related to the nature of pathogen. In addition, 34.39% of foreigners versus 90.97% of local students agreed that condom makes sexual intercourse safe in HIV acquisition. Contrary to Chinese students, whose source of information was mainly from school education, foreign medical students were more likely to use Internet; the majority of students reported an extracurricular training in HIV/STIs and almost all had wished to know more about HIV/AIDS.

Table 2: Knowledge and sources of information related to HIV/AIDS.

Items
Chinese students
Foreign students

value

Correct answers about HIV/AIDS

The pathogen of HIV/AIDS (virus)
265 (95.67)
78 (49.68)
127.87
<0.0001

The earliest time for HIV positive reaction after exposure (3 months)
76 (27.44)
65 (41.4)
8.91
0.00328

Most people exposed to HIV quickly show serious illness symptoms (No)
266 (96.03)
119 (75.8)
40.96
<0.0001

Reducing the number of sexual partner may protect from HIV/AIDS (Yes)
218 (78.7)
87 (55.41)
26.01
<0.0001

Condom makes sexual relation safe (Agree)
252 (90.97)
54 (34.39)
154.26
<0.0001

Individuals having only one sexual partner can not get HIV or STIs (No)
259 (93.5)
110 (70.06)
43.22
<0.0001

Keeping in good physical condition is the best way to prevent exposure to HIV/AIDS (No)
119 (42.96)
96 (61.15)
13.25
0.0003

Main sources of information about HIV/AIDS

Television or radio
126 (45.49)
110 (70.06)
24.39
<0.0001

School (lectures)
177 (63.9)
106 (67.52)
0.58
0.4472

Internet
145 (52.35)
113 (71.97)
16.01
0.0001

Friends
33 (11.91)
58 (36.94)
37.88
<0.0001

Spouse
25 (9.03)
18 (11.46)
0.67
0.4137

Doctor/nurse
65 (23.47)
53 (33.76)
5.36
0.0206

Books/newspapers/pamphlets and prints
139 (50.18)
82 (52.23)
0.17
0.6816

Other sources
31 (11.19)
22 (14.01)
0.74
0.3884

Assessment of HIV risky factors

Median score (IQR) of route of transmission
13 (12–14)
13 (12–14)
−1.99
0.0459

Median score (IQR) of high risk individuals
5 (4–6)
5 (4-5)
−3.54
0.004

Score of risk factors increasing HIV transmission
4 (3–5)
4 (3–5)
−1.01
0.3130

Previous extracurricular training in HIV and STIs
91 (32.85)
87 (55.41)
21.09
<0.0001

Self-assessment of sufficient knowledge on HIV/AIDS, syphilis, hepatitis, and tuberculosis
63 (22.74)
71 (45.22)
26.617
<0.0001

Students’ willingness to know more about HIV
226 (81.59)
140 (89.17)
4.361
0.0368

Only standard and correct answers were reported in this table, and subjected responses were discussed.

Correct answer scored 1 while wrong answer attributed 0.

is significant.

Confusions about route transmission and risk factors of HIV transmission were found among the two groups. Differences presented in Figure 1 showed that medical student knowledge remained inconsistent. Many students cited oral sex, mosquitoes bites, saliva, sweat, urine, tears, public health facilities, and physical contact as route of transmission of HIV (Figure 1(a)). Many also perceived students, healthcare providers, or migrants as high risk populations of HIV acquisition (Figure 1(b)); meanwhile despite the conventional known factors (blood manipulation, acquisition of STI, illicit drug addiction, etc.) which may increase HIV transmission, poverty or tobacco consumption was also enumerated to increasing HIV transmission (Figure 1(c)).

(a) Route transmission of HIV

(b) High risk individuals of HIV acquisition

(c) Factors increasing HIV transmission

Figure 1: Distribution of knowledge related to HIV transmission routes, high risk individuals of HIV acquisition, and factors increasing HIV transmission.

3.3. Attitude and Behavior of Medical Students towards People Infected with HIV/AIDS

Results given in Table 3 showed both difference and similitude of medical students’ attitude and behavior. 45.49% of Chinese students compared to 35.67% of foreigners opted to avoid condom usage after HIV testing of partners while 16.97% versus 22.93% agreed to have unprotected sex after mutual decision without HIV testing. Regarding the medical students’ attitude vis-à-vis their infected counterparts, the two groups of study population may react so differently and, however, 28.88% of Chinese students would prefer to keep away from the infected individual compared to 7.64% of foreigners. Similarly, participants exhibited the same attitude towards other people living with HIV/AIDS. Though the majority from each group expressed positive attitude of healthcare providers to support patients with HIV, only fewer admitted an intimate relationship between HIV infected individual and noninfected person. Furthermore, the large majority of students in the two groups have shown positive attitude of supporting HIV/AIDS patients in counseling, education, promoting the behavior change of population, or acting as peer educator; however, over 25% refused promoting patient rights and considered HIV infection highly dangerous comparing to syphilis, hepatitis B and hepatitis C, or tuberculosis.

Table 3: Attitude and behavior of medical students towards people infected with HIV/AIDS.

Chinese students
Foreign students

value

Avoidance of condom usage between partners

After HIV testing of both partners
126 (45.49)
56 (35.67)
16.27
0.001

After mutual decision without HIV testing
47 (16.97)
36 (22.93)

After marriage
63 (22.74)
22 (14.01)

Always been used
41 (14.8)
43 (27.39)

HIV/AIDS infection and ethnicity or culture
210 (75.81)
93 (59.24)
13.07
0.0003

Relationship between the development and the increase of HIV in China
1 (1-2)
2 (2-3)
7.54
<0.0001

    Yes
145 (52.35)
35 (22.29)

    Possible
98 (35.38)
57 (36.31)

    Probably
22 (7.94)
32 (20.38)

    Little/unlikely
5 (1.81)
20 (12.74)

    No
7 (2.53)
13 (8.28)

Attitude of students vis-à-vis of friend/classmate infected of HIV/AIDS

Inform university
29 (10.47)
10 (6.37)
57.21
<0.0001

keep far away from him/her
80 (28.88)
12 (7.64)

Assist him/her if needed
154 (55.60)
95 (60.51)

It is not my concern
14 (5.05)
40 (25.48)

It is unwise to be close to HIV infected person
73 (26.35)
37 (23.57)
0.41
0.5213

People infected of HIV/AIDS should stop attending school or working to be supported by the government and/or NGOs
108 (38.99)
35 (22.29)
12.64
0.0004

Students’ attitude towards people living with HIV

Must be isolated from other patients
44 (15.88)
45 (28.66)
10.04
0.0015

Should be punished by government
11 (3.97)
7 (4.46)
0.06
0.8067

Should be supported by healthcare providers
248 (89.53)
125 (79.62)
8.15
0.0043

Should be partnered with HIV negative
11 (3.97)
12 (7.64)
2.70
0.1008

Should be partnered with HIV positive
54 (19.57)
57 (36.31)
14.71
0.0001

Should never have a sexual partner
57 (20.65)
28 (17.83)
0.50
0.4779

Support of students towards HIV/AIDS matters

Promote the rights of HIV/AIDS patients
202 (72.92)
112 (71.34)
0.13
0.7225

Fight against stigmatization of HIV/AIDS
205 (74.01)
109 (69.43)
1.05
0.3053

Provide counseling and HIV testing to others
236 (85.2)
125 (79.62)
2.23
0.1353

Educate on safe sex practices
238 (85.92)
141 (89.81)
1.37
0.2420

Promote the behavior change of population
231 (83.39)
124 (78.98)
1.31
0.2523

Provide medical care to HIV/AIDS patients
204 (73.65)
118 (75.16)
0.12
0.7292

Act as peer educator of HIV/AIDS and STIs
226 (81.59)
114 (72.61)
4.76
0.0291

Classification and perception of HIV/AIDS and other surveyed infections: syphilis, hepatitis B, hepatitis C, and tuberculosis (median IQR)
1 (1–3)
1 (1-2)
−1.40
0.1621

(1) HIV is highly dangerous compared to other infections
236 (54.38)

(2) HIV is dangerous compared to other infections
92 (21.2)

(3) HIV is equivalent to other infections
89 (20.51)

(4) HIV is less dangerous than other infections
17 (3.92)

: Chi-squared; -value; is significant; IQR: interquartile range; HIV: human immune deficiency virus; AIDS: acquired immunodeficiency syndrome; NGOs: nongovernmental organisations; STIs: sexually transmitted infections.

3.4. Multiple Logistic Regression Analysis of Discrimination and Support of Medical Students towards People with HIV/AIDS and STIs Infected

From the multiple logistic regression analysis, results presented in Table 4 provided associations between medical students’ background and the negative or positive behavior vis-à-vis PLWHA. Age (OR: 0.09, 95% CI: 0.03–0.27), number of sexual partners (OR: 1.85, 95% CI: 1.10–3.12), recent HIV testing (OR: 2.45, 95% CI: 0.91–6.60), perceived medical students as high risk population (OR: 2.47, 95% CI: 1.01–6.03), and being informed through books and newspapers from HIV/AIDS (OR: 1.86, 95% CI: 1.10–3.17) were associated with the discrimination of people infected with HIV by medical students; and, however, Chinese medical students seemed to tolerate living with people infected with HIV/AIDS compared to foreign students (OR: 0.09, 95% CI: 0.03–0.27).

Table 4: Multiple logistic regression analysis of discrimination and support of medical students towards people infected with HIV/AIDS.

Variables
Estimate
SE
OR (95% CI)

Discrimination of people infected of HIV

Chinese students versus foreign students
−2.40
0.55
0.09 (0.03–0.27)

Age
0.16
0.04
1.17 (1.09–1.27)

HIV testing

    Tested 3 months before versus never tested
−1.41
0.63
0.24 (0.07–0.84)

    Tested 6 months before versus never tested
0.90
0.51
2.45 (0.91–6.60)

    Tested 1 year before versus never tested
−0.10
0.5
0.91 (0.34–2.41)

    Tested 2 years or more before versus never tested
−0.09
0.44
0.92 (0.39–2.16)

The number of sexual partners
0.62
0.27
1.85 (1.10–3.12)

Considered medical students under high risk of HIV
0.91
0.45
2.47 (1.01–6.03)

Opposed to physical contact transmission
−1.79
0.48
0.17 (0.07–0.42)

Condoms usage that completely protect against HIV
−1.11
0.36
0.33 (0.16–0.67)

Poverty as factor increasing HIV transmission
−0.84
0.29
0.43 (0.24–0.77)

Already discussed with doctor or nurse HIV/AIDS
−0.59
0.3
0.55 (0.31–1.00)

Reported books/newspaper as main source of information
0.62
0.27
1.86 (1.10–3.17)

Support to HIV infected individuals

Chinese students versus foreign students
1.33
0.5
3.78 (1.41–10.13)

Never been tested for hepatitis B
−1.03
0.36
0.36 (0.18–0.73)

Never been tested for hepatitis C
−0.69
0.32
0.5 (0.27–0.94)

HIV infection increase with biological fluid manipulation
0.65
0.28
1.91 (1.1–3.31)

HIV infected individuals do not show acute symptoms
2.25
0.48
9.47 (3.7–24.27)

Heterosexuals are in high risk of HIV acquisition
−0.67
0.32
0.51 (0.27–0.96)

Bisexuals are under high risk of HIV acquisition
0.59
0.25
1.81 (1.1–2.97)

Lack of awareness could increase HIV transmission
0.66
0.33
1.93 (1.02–3.65)

Poverty could increase HIV transmission
0.79
0.28
2.2 (1.28–3.79)

Acquisition of STIs would increase HIV transmission
−0.94
0.28
0.39 (0.22–0.68)

Tobacco and illicit drugs use could increase transmission
1.41
0.67
4.1 (1.1–15.36)

Condom usage could completely protect against HIV
0.97
0.35
2.62 (1.32–5.24)

Friends as main source of information on HIV/AIDS
0.73
0.36
2.07 (1.02–4.22)

Wanting to know more about HIV/AIDS
1.11
0.31
3.03 (1.66–5.55)

HIV: human immune deficiency virus; AIDS: acquired immunodeficiency syndrome; STIs: sexually transmitted infections; SE: standard error; OR: odds ratio; CI: confident interval.

Concerning the support to HIV infected individuals, several factors including students’ origin (OR: 3.78; 95% CI: 1.41–10.13), high level of knowledge about HIV transmission (OR: 1.91; 95% CI: 1.1–3.31), and manifestations (OR: 9.47; 95% CI: 3.7–24.27), being bisexual (OR: 1.81; 95% CI: 1.1–2.97), and vulnerability factors such as lack of knowledge about HIV/AIDS (OR: 1.93; 95% CI: 1.02–3.65) or poverty (OR: 2.2; 95% CI: 1.28–3.79), condom usage (OR: 2.62; 95% CI: 1.32–5.24), source of information (OR: 2.07; 95% CI: 1.02–4.22), and the willingness to know more about HIV/AIDS (OR: 3.03; 95% CI: 1.66–5.55) were associated with the support that students may provide to HIV/AIDS individuals; however, never having been tested (OR: 0.36; 95% CI: 0.18–0.73) or vaccinated for hepatitis B (OR: 0.5; 95%: CI 0.27–0.94) and knowing that STIs acquisition increase HIV transmission (OR: 0.39; 95% CI: 0.22–0.68) could negatively affect students’ behavior vis-à-vis HIV infected individuals.

4. Discussion

4.1. Participants’ Background, HIV/AIDS, and STIs Knowledge

Human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS) are known as a major public health concern worldwide. The constant assessment of healthcare provider knowledge and behavior would always contribute to overcoming the infection. No previous study has assessed and compared medical student’s knowledge and behavior towards HIV/AIDS and associated sexually transmitted infections among local students and their foreign counterparts in China. Whether differences were found across countries in students’ knowledge, attitudes, and behavior [22–24], medical students are the milestone of healthcare providers. No matter where they are from and were trained, they are in the forefront of medical care and may play a key role in different health areas as well as in globalization health. Though all participants were sexually active, no difference regarding education level existed among the survey population. However, major differences were observed between the two groups. Chinese students were slightly older than foreigners and many were currently engaged with sexual partner. This result may be obviously due to the stability of participant that provides consistent reasons to feel close and project common goals between Chinese students.

This study revealed high rate of homosexuals among Chinese students compared with foreigners. Despite the fact that homosexuality is contrary to Chinese values and not yet accepted, some Chinese young men and women are sexually going with the same sex partner [9]. Of note, HIV transmission is mainly drawn by MSM in China [5]. However, recent studies reported that HIV transmission is shifting into heterosexual populations [2, 8, 10, 25]. Foreign students were more likely to have more than one sexual partner with inconsistent condom use certainly because they feel uncomfortable with condoms. Despite the missing information on casual sex intercourses of participants, we speculate that instability previously described may lead foreigners to experience more occasional relations contrary to Chinese students. Results of HIV, syphilis, hepatitis, and tuberculosis testing history showed that almost all foreigners had been tested for HIV while only fewer Chinese medical students were aware of their HIV status. Similar observation occurred when assessing syphilis, hepatitis, and tuberculosis screening history. The difference observed is certainly resulting from the Chinese government requirements for foreigners to have physical examination for communicable diseases including HIV/AIDS, syphilis, hepatitis, and tuberculosis before coming to China or applying for temporary residency. Despite the medical status of participants, findings revealed independently of education level and region of origin that student’s sexual behavior is questionable and merits changes regarding their risk exposure to HIV and STIs.

Despite the greater effort made by international organisations, nongovernmental organisations, and the majority of governmental institutions in developing world to inform and educate about communicable diseases, several misconceptions are persistent among students including medical students on HIV/AIDS and STIs [18, 26, 27]. Independent of their education level and region of origin, this study showed a huge gap in participants’ knowledge. For example, almost all Chinese students provided the right answer when identifying the nature of AIDS pathogen compared to less than half of foreigners; concerning the earliest related time for HIV positive testing after exposure only forty-one per cent of foreigners identified the right answer compared to twenty-seven per cent of Chinese students. More than eighteen years after Cook et al. found discrepancies in HIV knowledge among medical students and suggested innovative methods to improve students’ awareness on HIV [14], confusion and misconception still remain. In this study, more than twenty per cent of medical students reported mosquitoes bites, tears, saliva, and public facilities as transmission route while about forty per cent cited poverty as factor increasing HIV transmission. The education level and extracurricular training on HIV/AIDS of participants were critical to clearly provide accurate responses; however, not being excellent everywhere, Chinese students were more knowledgeable than foreigners. The difference that we found here may partly come from the language barrier for foreigner to extend the information sources on the studied diseases. In accordance with other previous studies [15, 16, 18, 27], this finding highlighted the need of reinforcing medical student background on HIV/AIDS and STIs especially among foreigners studying in Chinese universities who noticeably showed greater interest to know more about the studied infections.

4.2. Attitude and Behavior of Medical Students

Though personal conception can significantly impact individual’s behavior, medical students along their education are sufficiently trained and confronted by different illness cases that may offer opportunities to show much positive attitude vis-à-vis all patients regardless of the nature of infection. In this study, forty-five per cent of Chinese medical students compared to thirty-six per cent of foreigners preferred to avoid condom use after HIV testing. Thus, the great proportion would allow unprotected sexual intercourse among unknown HIV status person; however, this study found a lower rate of HIV testing among local students. In fact, several previous studies demonstrated the missed opportunities of medical students and healthcare providers to uptake HIV and STIs testing of populations [6, 13, 19, 27, 28]; and, moreover, many other studies reported that millions of people including medical students with unknown serology are infected with HIV and STIs [29, 30]. So, students personal sexual risk behavior may affect their decision-making towards HIV and associated diseases testing. In this study, though three-fourths of local students never tested for HIV, a significant proportion perceived a link between the development of China and the increase of HIV prevalence. Anyway, a recent study showed an increase of the prevalence of HIV/STIs in China [5]. Perception in our study population could be originated from the unexplained students’ beliefs of association between ethnicity and HIV infection. Once again, education and attitude of medical students merit being canalised with accurate and consistent training on HIV/AIDS to overcome the global epidemic.

Although all participants exhibited the willingness to support HIV individuals through several actions, about twenty-nine per cent of Chinese medical students prefer to stay away from classmate or colleague infected with HIV while twenty-four per cent of foreigners though it was unwise to be close to HIV infected person. According to this finding, we suggested that medical student training time period is an opportunity to identify and correct negative attitude leading to discrimination of HIV infected individuals found within participants. More importantly, this study revealed that age, number of sexual partners, HIV testing, considering oneself as high risk individual to HIV, considering physical contact as route of transmission, poverty, and having only books and newspapers as main source of HIV/AIDS information were factors that increased discrimination of people infected with HIV by medical students; however, deeper knowledge subsequently increases medical students’ support towards people living with HIV/AIDS and STIs. In accordance with previous studies [8, 15, 17, 31], an overlap misconception, confusion, and fears may lead medical students to discriminate and provide poor medical care towards people infected with HIV and STIs infected individuals. Overall, this study provided substantial evidence of reinforcing education of medical students on HIV/AIDS and STIs with a particular interest in foreign students who are limited in HIV/AIDS information. Therefore, we suggest the introduction of HIV/AIDS and STIs activities through short training, debate, conference, workshops, and symposia in medical student curricula.

4.3. Limitations

Several limitations appear to this cross-sectional study in nature. Although all participants were sexually active medical students, they had different background and culture that may affect the disclosure of attitude and behavior. The authors have limited the recruitment of participants to a single university out of numerous universities in China. Therefore, the extension and further clinical observational studies are warranted to assess students’ knowledge, attitude, and behavior described in the current study.

5. Conclusions

This study has established the overview of knowledge, attitude, and behavior on HIV/AIDS, syphilis, hepatitis B and hepatitis C, and tuberculosis among medical students in Chinese university. Chinese students scored high level of knowledge compared to foreigners while several misconceptions, confusion, and fear existed among the two groups. Students’ background and sexual activity strongly affected their attitude and behavior towards people infected with HIV and STIs. The present study arouses much interest among participants and implies the need of reinforcing medical students’ education on HIV/AIDS and sexually transmitted infections.

Competing Interests

The authors declare that they have no competing interests.

Authors’ Contributions

Martin Kuete and HuiPing Zhang conceptualized and designed the study materials. Martin Kuete, Xiu Lan Ma, Abid Rashid, HongFang Yuan, Qian He, and Qiao Huang were involved in the acquisition of data. Martin Kuete, Abid Rashid, and Qiao Huang performed the statistical analysis. Martin Kuete, Abid Rashid, and Qiao Huang drafted the paper. Rakhmanov Yeltay, Juan Pablo Escalera Antezana, ChengLiang Xiong, HongFang Yuan, Xiu Lan Ma, and Meng Rao revised the draft paper for intellectual content. HuiPing Zhang and ChengLiang Xiong supervised the study. All authors read and approved the final paper. Martin Kuete, Qiao Huang, and Abid Rashid equally contributed to this work.

Acknowledgments

The authors gratefully acknowledge the awards from Anhui Biochem Pharmaceutical Company of China and Family Planning and Research Institute of Tongji Medical College. They also thank all students involved for their contributions.

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