BioMed Research International
Volume 2016 (2016), Article ID 6240750, 2 pages
http://dx.doi.org/10.1155/2016/6240750

Corrigendum

Corrigendum to “Magnesium Lithospermate B, an Active Extract of Salvia miltiorrhiza, Mediates sGC/cGMP/PKG Translocation in Experimental Vasospasm”

Chih-Zen Chang,1,2,3 Shu-Chuan Wu,² and Aij-Lie Kwan1,2

¹Department of Surgery, Faculty of Medicine, School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
²Department of Neurosurgery, Kaohsiung Medical University Hospital, No. 100, Tzyou 1st Road, Kaohsiung 80752, Taiwan
³Department of Surgery, Kaohsiung Municipal Ta Tung Hospital, Kaohsiung, Taiwan

Received 28 December 2015; Accepted 12 January 2016

Copyright © 2016 Chih-Zen Chang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

In the paper titled “Magnesium Lithospermate B, an Active Extract of Salvia miltiorrhiza, Mediates sGC/cGMP/PKG Translocation in Experimental Vasospasm” [1] in Figure (a) we mistakenly used the same Western blot for RhoA, membrane portion, and ROCK II. The corrected figure and legend are presented here.

In Figure , we mistakenly used the same Western blot for β-actin and PKCδ. The corrected figure and legend are presented here.

Figure 2: Inhibitory effect of MLB on RhoA translocation (a) and ROCK II expression (b) in the BAs. Expression of RhoA in the cytoplasm and membrane as well as ROCK II was also determined by Western blot analysis. (A) The healthy controls, (B) the vehicle-treated SAH rats, and (C) SAH rats received 10 mg/kg/day MLB treatment, (D) SAH rats received 10 mg/kg/day MLB preventive treatment, and SAH rats received both 10 mg/kg/day MLB pretreatment and 1 mg/kg L-NAME as (E) (upper panel). The ratio of membrane bound to cytoplasm RhoA in the SAH group was set at 100% in (a), whereas the expression of ROCK II (normalized using β-actin) was set the same in (b). Data are mean ± SEM (/group). , versus the vehicle +SAH, MLB, and L-NAME groups, respectively.

Figure 4: Suppressed PKCδ translocation by MLB in the BAs. The bioexpression of PKCδ from the cytoplasm to membrane was determined by Western blot analysis. The ratio of membrane bound to cytoplasm PKCδ in the SAH group was set at 100%. Data are shown as mean ± SEM (/group). , the vehicle +SAH versus sham and MLB prevention groups, respectively, and : compared with SAH rats pretreatment with MLB and L-NAME. All groups are identical to those shown in the legend of Figure 2.

References

C.-Z. Chang, S.-C. Wu, and A.-L. Kwan, “Magnesium lithospermate B, an active extract of Salvia miltiorrhiza, mediates sGC/cGMP/PKG translocation in experimental vasospasm,” BioMed Research International, vol. 2014, Article ID 272101, 9 pages, 2014.