Children with severe hearing loss most likely receive the greatest benefit from a cochlear implant (CI) when implanted at less than 2 years of age. Children with a hearing loss may also benefit greater from binaural sensory stimulation. Four children who received their first CI under 12 months of age were included in this study. Effects on auditory development were determined using the German LittlEARS Auditory Questionnaire, closed- and open-set monosyllabic word tests, aided free-field, the Mainzer and Göttinger speech discrimination tests, Monosyllabic-Trochee-Polysyllabic (MTP), and Listening Progress Profile (LiP). Speech production and grammar development were evaluated using a German language speech development test (SETK), reception of grammar test (TROG-D) and active vocabulary test (AWST-R). The data showed that children implanted under 12 months of age reached open-set monosyllabic word discrimination at an age of 24 months. LiP results improved over time, and children recognized 100% of words in the MTP test after 12 months. All children performed as well as or better than their hearing peers in speech production and grammar development. SETK showed that the speech development of these children was in general age appropriate. The data suggests that early hearing loss intervention benefits speech and language development and supports the trend towards early cochlear implantation. Furthermore, the data emphasizes the potential benefits associated with bilateral implantation.
Best practice with regard to the timing of cochlear implantation continues to evolve as recent findings reveal convincing data related to the time of implantation and the achievement of maximum benefit for the young (<2 years old) [
It appears early implantation makes it possible for children with a hearing impairment to perform as well as their hearing peers in terms of speech and language development. Tomblin et al. [
Further evidence indicates that a “sensitive” or “critical” period in speech and language development exists, during which implantation has the greatest potential impact [
Unilateral amplification of bilateral hearing loss has been shown to be associated with limited auditory function [
The purpose of this case study investigation was to describe the overall functioning over time of four children receiving bilateral cochlear implants at a young age (<2 years old). It was our aim to document and review the general auditory and speech behavior of these children.
Four children with a prelingual hearing loss (3 boys and 1 girl) were recruited from the Department of Otolaryngology and Cochlea Implantat Centrum (CIC) Süd, Würzburg, Germany, and enrolled in this longitudinal study. All children were being raised in a monolingual German speaking environment and no additional needs were reported. The etiology of congenital deafness of 3 children was unknown; one child (Case 3) had heredofamilial hearing loss. All the children had undergone cochlear implantation, before the chronological age of 12 months and were fitted with a MED-EL COMBI40+ and a behind the ear TEMPO+ speech processor. In all cases, the first fitting for both CIs took place within 1.5 months after implantation and no surgical complications were reported. The cognitive evaluation and speech and language assessment were undertaken in the rehabilitation center CIC Süd, where the children received auditory-verbal therapy in group and individual sessions. Audiological evaluations were at regular intervals in the Audiology Unit at the Department of Otolaryngology.
A parent or guardian gave written informed consent for each child at audiological assessment.
For the purposes of this study it was important to rule out the presence of additional needs in overall intellectual functioning amongst children; thus, the data could be used comparatively to evaluate other children with the same degree of hearing loss and normal cognitive function. Nonverbal intelligence testing is a standard component of evaluations for patients seen at the CIC. Testing could only take place once the subjects had reached the lower age limits for which the tests were appropriate. In order to assess intellectual functioning with minimal interference of language skills, the children were tested with the SON-R
A complete battery assessing auditory behavior and speech development was performed at regular test intervals; beginning with unilateral testing and then bilateral once a second CI was fitted. The battery consisted of the LittlEARS Auditory Questionnaire [
The aided free-field thresholds were measured using visual reinforcement (COR) and sound localization responses. Furthermore, the children were asked to localize a signal delivered at MCL through one of four loudspeakers arranged at 90°, 45°, −45°, and −90°.
Speech audiometry was performed in a sound proof booth with the “Mainzer Kindersprachtest’’ [
The Göttinger is a German speech perception test for children aged 3-4 and 5-6 years. It comprises lists of words that the child being tested must repeat. Children can use picture cards to identify the words presented to them.
Reactions to sounds and speech perception abilities were tested with the Listening in Progress Profile (LiP), the Monosyllabic-Trochee-Polysyllabic (MTP) test, and closed- and open-set monosyllabic word tests. These tests are part of the evaluation of auditory responses to speech (EARS) test battery [
The LiP was used to assess the subjects’ auditory detection, discrimination, and early identification abilities of environmental sounds and speech (at the single word or phoneme level); LiP scores were reported as percentage correct. The MTP test is a closed-set test used to assess the ability of an individual in recognizing words with different syllabic patterns. These tests were performed in a quiet room under normal ambient noise conditions.
To investigate the speech development of the children in the present case series the “Sprachentwicklungstest” (SETK) was used [
The TROG-D is a German adapted test which aims to determine the reception of grammar in children aged 3–10;11 years [
The AWST-R [
The interpretation of referenced test results was performed via comparison to a normative group of hearing children. The values of the normative group are represented as T-values and percentage range for a given test, which is determined and provided by the test developer. The T-values of the CI children were compared to the mean normative T-values of the hearing children. Results of TROG-D, AWST-R, SETK-2, SETK-3–5, and SETK-4-5 are depicted in a table format.
Except for the severe hearing loss the subjects were neurologically and intellectually age appropriate as determined by the SON-R 2.5–7 nonverbal intelligence test (see Table 1 in Supplementary Material available online at
The female subject was implanted at the age of 9;24 months, and the first fitting was performed at the age of 11;26 months of age in the left ear, following 1-month hearing aid experience with no listening progress. The child had no preoperative speech perception skills at the beginning of this study. Initial fitting on the right ear called for louder levels until the maximum was reached and the need arose for the fitting of a second CI at 18 months of age in the left ear. At this point, stimulation on the right side was reduced and fitting levels remained stable.
Auditory development as determined by the LittlEARS Auditory Questionnaire improved from a score of 0 preoperatively to 1 at the first interval to a score of 14, 21, 26, and 31 at subsequent intervals (Figure
Auditory development as determined by the LittlEARS Auditory Questionnaire ((a)–(d)). The solid line denotes the German derived normative curve. The dashed line represents the minimum 95% confidence interval values from the German-derived norms. Filled triangles denote the score of children (
Prior to implantation the child’s aided responses with the hearing aids were at 0.5−1 kHz 70 dB with a steep drop at 2–4 kHz to 90 dB. Four months after the first fitting of the implanted side aided responses with the CI were at 0.5–4 kHz 40–45 dB. Similarly, aided responses in free-field showed continuous improvement. Ten months after the first fitting of the first CI and 2 months after the fitting of the second CI the child reacted at 0.5–4 kHz at 25–35 dB.
Sound localization abilities also showed continuous improvement following the fitting of the second CI. After 6 months of experience with the first CI the child was unable to localize sounds correctly, from 90 and −90 loudspeakers. Two months after the fitting of the second implant the child was able to localize 100% of the signals offered from all 4 loudspeakers. This was consistent after 6 and 12 months of binaural hearing experience.
Twenty-two months after the first fitting of the first CI the child was able to reach an 80% word discrimination score at 70 dB on the Mainzer Test (mono- and bisyllabic words). At a hearing age of 30 months the child’s word discrimination score was 90% at 70 dB on the Göttinger test (monosyllabic words).
At follow-up LiP percentages correct were 10% at first fitting, 23% after 3 months, 31% after 6 months, 66% after 12 months, and 66% after 15 months CI experience (Figure
Listening Progress Profile (LiP) at follow-up, preoperatively (preop), at 1-month and at 3-month intervals. LiP scores are reported as percentage correct.
MTP testing at the 12-word level was 100% at the 18-month interval. At 24 months the child had reached 100% in the monosyllable test (closed-set) and 50% discrimination for monosyllables in the open-set test. At 31 months she reached a score of 100% in the open-set monosyllables test.
At the age of 2;11 years SETK-2 showed that the child’s “Word Comprehension” “Sentence Comprehension”, and “Word Production” were within the normative range of hearing children (Table
Outcomes of age-appropriate speech development tests SETK-2, SETK-3–5, and SETK-4-5, presenting
Case 1 | Case 2 | Case 3 | Case 4 | |
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SETK-2 | ||||
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Comprehension I and II: | ||||
Word comprehension | 45 (30.8) | 54 (65.5) | 61 (88.5) | 54 (65.5) |
Sentence comprehension | 41 (18.4) | — | 41 (18.4) | 54 (65.5) |
Speech production I and II: | ||||
Word production | 47 (38.2) | 76 (99.5) | 56 (72.6) | — |
Sentence production | 34 (5.5) | — | — | — |
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SETK-3–5 | ||||
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Sentence comprehension | 50 (50.0) | 55 (69.2) | 50 (50.0) | — |
Encoding semantic relations | 45 (30.9) | — | 65 (93.3) | — |
Morphological syntax | 42 (21.2) | 62 (88.5) | — | — |
Phonological working memory for nonsense words | 39 (13.6) | 57 (75.8) | — | — |
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SETK-4-5 | ||||
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Sentence comprehension | 55 (69.2) | 62 (88.5) | 53 (61.8) | 47 (38.2) |
Morphological syntax | 39 (13.6) | 63 (90.3) | 41 (18.4) | 64 (91.9) |
Phonological working memory for nonsense words | 46 (34.5) | 43 (24.2) | — | — |
Memory span (word) | 38 (11.5) | 58 (78.8) | 49 (46.0) | 55 (69.2) |
—indicates child was not tested or refused cooperation at this test interval.
% indicates percentile rank.
At the age of 3;11 years SETK-3–5 testing indicated that the child’s “Sentence Comprehension”, “Encoding of Semantic Relations”, and “Morphological Syntax” were within the range of the normative hearing group (Table
With 4;7 years of chronological age the SETK-4-5 was conducted (Table
In the TROG-D test, conducted at 4;10 years of age the child reached a
Outcomes (
Case 1 | Case 2 | Case 3 | Case 4 | |
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(a) Reception of grammar: |
54 (64.0) | 54 (65.0) | 54 (64.0) | 57 (77.0) |
(b) Active vocabulary: |
49 (48.0) | 56 (73.0) | 50 (95.0) | 42 (45.0) |
In the vocabulary test AWST-R, conducted at the age of 4;8, years the child’s performance was within the normative range of hearing children (Table
The male subject presented was implanted at the age of 10;10 months on the right side and 19;1 months on the left side. Prior to fitting the child had no hearing experience, despite the use of hearing aids on both sides since the age of three months. Within days of the first fitting the right CI was increased by 30% of the original stimulation levels. After fitting the left CI (at approximately the 8-month interval) the stimulation levels, on the right CI, were reduced to the original fitting parameters.
Out of 35 questions on the LittlEARS Auditory Questionnaire results improved from 7 at the first interval to 24, 26, and 31 at consecutive intervals. As shown in Figure
Prior to implantation the child’s aided responses with the hearing aids were at 0.5 kHz 85 dB, at 1 kHz 80 dB, and at 2 kHz 90 dB. Three months after fitting of the first implant the child’s aided responses with the CI were at 0.5–4 kHz 30 dB. Aided responses remained stable throughout the follow-up period.
The child’s sound localization abilities showed continuous improvement following the fitting of the second CI. Four months after the fitting the second implant the child was able to localize 75% of the signals offered correctly, from all 4 loudspeakers. This was consistent after 6 and 9 months of binaural hearing experience.
Thirteen months after the first fitting of the first CI the child reached 80% word discrimination scores at 70 dB on the Mainzer Test (mono-and bisyllabic words). At a hearing age of 20 months his word discrimination score at 70 dB on the Göttinger test (monosyllabic words) was 80%.
Likewise, listening and perception of speech and environmental sounds improved as determined by LiP test score. Compared to 14% preoperatively the LiP score was 24% at the first fitting, 52% at 3 months, 52% at 6 months, and 66% after 12 months (Figure
MTP test results identifying speech patterns at the 12-month interval indicated 100% of both the 3-word and the 3-pattern subtests were correct and 84% on the 6-word subtest and 89% on the 6-pattern subtest. At the 15-month interval MTP performance in the 6-word and 6-pattern subtests increased to 100% and testing of both the 12-word and pattern level were 67% correct. At the 22-month interval, 100% of the words on the 12-word subtest, which is the most advanced level of difficulty for the MTP test, were correct. This was an improvement from 67% at the 15-month interval on the same test. At 24 months the child has reached 100% on the monosyllable test (closed-set) and 70% discrimination on the open-set monosyllables test. At 28 months he reached 100% on the open-set monosyllables test.
At the age of 2;3 years the SETK-2 was conducted (Table
At 3;11 years the SETK-3–5 was conducted (Table
At the age of 4;10 years the SETK-4-5 (Table
At 5;2 years the TROG-D, used to determine the child’s understanding of grammar, was within the normative range of hearing children (Table
Likewise, at the same age the vocabulary as determined by AWST-R indicated that the child was within the normative range of his hearing peers (Table
The male subject presented was fitted with hearing aids at 3 months of age with no apparent benefit. He was first implanted in the right ear at 4;21 months with a CI and then contralaterally at 16 months of age.
In the LittlEARS Auditory Questionnaire the child achieved a score of 0 at the first interval and a score of 14, 17, 21, 25, 32, 33, 32, and 34 at subsequent intervals (Figure
Prior to implantation the child showed minimal response with a hearing aid. In free-field the child’s reactions with both hearing aids were inconsistent at 0.5, 1, and 2 kHz at 100–120 dB. Three months after fitting the first implant the child’s aided responses with the CI were at 0.5 to 4 kHz 65–80 dB. His aided responses in free-field continued to show an improvement. Six months after the first fitting of the first CI he reacted at 45–55 dB. Eighteen months after the first fitting of his first CI and 6 months after the fitting of his second CI the child reacted at 35–40 dB. The child’s aided thresholds remained stable throughout the rest of the follow-up period.
The child’s sound localization abilities showed a continuous improvement following the fitting of the second CI. Six months after the fitting the child was able to localize 100% of the signals offered from all 4 loudspeakers. This was consistent after 9 and 18 months of binaural hearing experience.
Twenty-eight months after the first fitting of the first CI the child reached an 80% word discrimination scores at 70 dB on the Mainzer Test (mono-and bisyllabic words).
The scores of the LiP profile were as follows: 0% preoperatively, 4% at the 1-month interval, 6% at 3 months, 28% at 6 months, 52% at 12 months, and 62% at the 18-month interval (Figure
The score reached on the MTP test was 100%, on the 3-word and 6-word tests, at the 12- and 18-month intervals. The child scored 100% on the MTP 12-word test at the 24-month interval. At the same interval (24 months) the child scored 80% on the open-set monosyllable test. At the 28-month interval the child reached a score of 100% on the closed- and open-set monosyllable tests.
When the child was 2;10 years old the SETK-2 was conducted (Table
At the chronological age of 3;4 years the “Sentence Comprehension” of the child determined by SETK-3–5 (Table
At 4;0 years of age the SETK 4-5 was conducted (Table
At the chronological age of 4;3 years the grammatical test TROG-D was conducted. The child’s performance was within the normative range of hearing children (Table
The vocabulary test AWST-R conducted at an age of 3;8 showed the child’s performance was higher than the average of the normative hearing children group (Table
The male subject was fitted with hearing aids at the age of 4 months. Following the hearing aid trial, the child received his first CI on the right side at the age of 6;15 months and experienced the need for louder and louder settings at fitting, until a contralateral CI was fitted shortly after the 12-month interval. Stimulation rates on the right side were subsequently decreased by 10%. No alterations to the initial fitting parameters of the second CI, on the left side, were made.
The LittlEARS Auditory Questionnaire determined that auditory performance, which was 0 preoperatively, improved from a score of 10 at the first interval to scores of 20, 26, 30, 35, 34, and 35 at subsequent intervals (Figure
Prior to implantation the child showed hardly any response with the hearing aid. In free-field the child did not show any consistent reactions to sounds presented at maximum intensity (120 dB). Three months after fitting the first implant the child’s aided responses with the CI were at 0.5–4 kHz 55–70 dB. The child’s aided responses in free-field slowly, but continuously, improved over time. Six months after the first fitting of the first CI the child reacted at 50–80 dB. Twenty-four months after the first fitting of the first CI and 15 months after the fitting of the second CI the child reacted at 0.5 to 8 kHz at 30–35 dB. The aided thresholds remained stable throughout the rest of the follow-up period.
The child’s sound localization abilities showed continuous improvement following the fitting of the second CI. After five months the child was able to localize 90% of the signals offered from all 4 loudspeakers. At 8 and 12 months of binaural hearing experience the child was able to localize 100% of the sound sources.
Twenty-one months after the first fitting of the first CI the child reached 90% word discrimination at 70 dB on the Mainzer Test (mono- and bisyllabic words). At a hearing age of 24 months discrimination scores on the Göttinger Test (monosyllabic words) were 50%.
Scores on LiP testing were 0% preoperatively and at the 1-month interval; 21% at the 3-month interval; 42% at the 6-month interval; and 57% at the 12-month interval (Figure
The MTP 12-word score obtained at the 18-month interval was 100%. At 18 months the child also reached 100% on the monosyllable test (closed-set). At a hearing age of 24 months, discrimination of open-set monosyllables was 80%.
At the age of 2;5 years the single subtests of SETK-2 were conducted (Table
At 4;4 years of age the SETK 4-5 determined that the child had greater than average performance in the “Morphological Syntax” subtest compared to the normative range of hearing children (Table
At 4;8 years of age the child’s understanding of grammar tested via TROG-D revealed that his performance was within the normative range of hearing children (Table
Similarly, according to AWST-R the subject’s vocabulary at 4;6 years was within range when compared to the normative group (Table
Cochlear implantation in children under 2 years of age aims to expose children with a hearing loss to spoken language via hearing, thus, minimizing the gap between chronological age and the development of language skills that may occur in children with a hearing loss compared to their hearing peers [
Growth curves of the children, reflected in the results of the LittlEARS battery, show individual differences in each child’s progress and rapid development. All achieved age-appropriate auditory skills compared to the normative range of hearing children, as determined by the LittlEARS Auditory Questionnaire, by 20 months of age (range = 10–20 months). This supports the findings of Tomblin et al. [
Early exposure to auditory stimuli via cochlear implantation under 2 years affords children with greater access to spoken language via hearing, which promotes a subsequent increase in auditory and linguistic skills and speech understanding [
The data described in the present study is suggestive of a sensitive period. All children were bilaterally implanted before 2 years of age and showed “Word Comprehension” and “Sentence Comprehension” abilities within the normative range of hearing children when followed up by SETK-2. Likewise, “Word Production” tested by SETK-2 was within the range of hearing children. By the time of SETK-4-5 all the children’s performance in “Sentence Comprehension” were within, or above, the normative range of hearing children and the same applied for “Speech Repetition” in three out of four of the children. The fourth child’s “Speech Repetition” fell only marginally below that of the normative group. Similarly, Vlastarakos et al. has shown that age at implantation shows the greatest influence on speech perception, speech production, and language outcomes in children implanted with a CI between 1 to 72 months of age [
Given the evidence indicating that the development of language skills, in children with a prelingual hearing loss, requires several years to follow-up [
The data presented in this series illustrates each individual child’s educational and social needs. This emphasizes the need to consider the appropriateness of habilitation for each child on an individual basis. We suggest that, according to the results herein, cochlear implantation with a CI at less than 2 years of age may be of significant benefit to children with a hearing loss. It appears that the children gain in auditory, speech, and grammar development upon the use of a CI. The potential benefits support the trend toward early cochlear implantation. Furthermore, as the children included in this study were all bilateral CI recipients, the data emphasizes the potential benefits associated with bilateral implantation. Although we did not specifically address differences in unilateral versus bilateral implantation, we can conclude that the bilateral implantation has contributed to the capacity of the children to develop age-appropriate auditory speech and language skills.
The authors declare no conflict of interests.
The authors would gratefully like to acknowledge Joanna Brachmaier and Una Doyle, from MED-EL GmbH, for their writing assistance.