New products

and needle homogenization techniques. The homogenized lysate sample is then ready for RNA extraction. Employed as a single-use consumable, the Chromatrap Homogenizer Spin Column eliminates the possibility of sample cross-contamination. Fully compatible with all manual RNA extraction kits, the Chromatrap Homogenizer Spin Column provides an ideal sample preparation solution for RNA miniprep and midiprep. Chromatrap For info: +44-(0)-1978-661144 www.chromatrap.com/homogeniser-spin-column

'open architecture' principles, making it compatible with most laboratory instruments. Data can be collected and processed direct from the instrument via serial communications or a network. The software supports up to eight separate channels, data from which may be viewed collectively or independently. The speed of acquisition easily copes with kinetics and real-time chromatography or spectroscopy. Alternatively, Lab Calc can be used off-line, working on data stored in DOS files, or with data collection continuing in the background.
The real-time graphics capability allows both two-and three-dimensional data to be viewed with a contour representation that may be zoomed, expanded and rescaled interactively. Up to 30 levels of contour lines may be displayed in up to eight colours. Multi-level, menu-driven operation makes Lab Calc easy to use, with a choice of pop-up windows or standard horizontal menus.
Extensive on-line help is included.
The data processing capabilities of the package are extensive and include all standard number-crunching routines as well as less usual functions such as polynomial baseline subtraction and adjustment of 28O raw chromatograms to observe runto-run retention time differences.
The software includes a large library of pre-programmed data processing applications, which, coupled with Galactic's complete scientific data manipulation language, provides the tools for a range of customized functions.
Lab Calc's multi-dimensional datahandling capacity enables the system to process the huge data sets generated by hyphenated techniques such as diode-array/LC, GC/IR and LC/ IR, as well as 2D NMR. Chromatograms can be extracted from timeresolved, multi-spectral runs and spectra extracted from multidetector chromatographic runs.
Multiple chromatograms or spectra can be overlaid for comparison, and both chromatographic and spectral data may be viewed simultaneously. Peak positions and edges, amplitudes, areas, percentage areas, concentrations and compound names can be shown, and peaks labelled with retention time, area and other peak table information.
A menu-driven method editor allows sophisticated chromatographic methods including instrument control functions to be constructed. These methods may incorporate fast peak picking and integration, timed events, baseline override, forced peaks, negative peaks and advanced auto-injector and pump control.

Chromatography vial data-sheets
Chromacol has started publishing a series of data-sheets showing the compatibility of their chromatography vials with leading autosampler brands. The first two are available for the LDC Promis and Marathon, and also the Spark Promis and Marathon. Information is based on tests performed in the laboratory of either the respective instrument company (or one of the official dealers) using Chromacol's standard glass and plastic vials, as well as their new 'Gold' range. The necessary caps and seals are also described. The data-sheets include a reference chart on the compatibility of the seals with a range of typical chromatography solvents. (1) Protein purification.
A column selection guide included in the brochure lists suitable columns and explains why and how a particular material should be used. The brochure clarifies the misconception that only one class of columns--glass columns--is right for biological molecules such as proteins and peptides. A full list of HP columns in glass and stainless steel completes the guide.
The brochure documents many separations developed on HP instruments in industry and academia with a list of references to the literature. A feature of the IKAVISC equipment system have been combined into one unit. The twist in the torsion bar is used to convert into an actual torque readout through the electronic measuring system. The signals from the torque sensor are processed and a readout given on the large digital display.
In addition to a measuring mode, the versatility of the IKAVISC equipment is extended with its 'limit' alarm feature. Two alarm settings. can be selected. An optimum 'limit' can be selected, as can an upper or lower value. When either the upper or lower limit is exceeded an alarm can be triggered. This alarm output, apart from giving an audible warning, can be used to trigger valves etc., in such applications as batching. Philips analytical Chromatography's PU4247 HPLC autosampler complements the company's range of modular, isocratic and gradient pumps. Key features of the autosampler are reproducible injection volumes with minimal carry-over, together with ease of use and reliability. Loop flushing is performed by head space pressure in combination with a metering, flow-through dispenser, making the system economic with sample volumes. Only flushed loop injections are used. The pneumatic actuator system is dependable an@st, with a switching time of less than 50 ms. In addition, there is a fixed connection between the sample needle and injector, which means there is no troublesome combination of loop filler ports with septum needles. The autosampler features an RS232 interfacefor data transfer to an integrator or laboratory computer. It also has inputs and outputs at TTL level for remote startfor next vial and injection, and a BCD output for the vial number. An inert gas blanket for the Linomat IV protects oxia-t-ion-prone samples or their components against attack by atmospheric oxygen while being sprayed on. The stream of nitrogen propelling the sample will not, on its own, protect sensitive substances. By a kind of water-jet pump action, the sprayjet sucks in air and hence oxygen molecules, which make intimate contact with thejqnely dispersed spray mist and can react with substances sensitive to oxidation. This is prevented if spraying on is effected under a blanket of nitrogen. In addition, during spraying on of successive samples, the starting zones of the samples already applied remain under inert gas protection.

Automatic dissolution
Dissolution testing is widely used in the pharmaceutical industry for formulation testing and as a qualitycontrol parameter. Perkin-Elmer now offers a PC-controlled automatic system based on UV/Vis spectrome-tric detection of the active compounds. Sampling is done by parallel, continuous or intermittent sample flow from up to eight dissolution vessels in closed loops. The Perkin-Elmer Dissolution Software (PEDS) package controls the full system based on USP and GLP recommendations. Functions include spectrum scanning, multi-wavelength calibration, result manipulation and data export. All parameters are stored on disk as a parameter file and all raw data are automatically saved on disk for post-analysis evaluation. PEDS offers command chaining for optional automation of operations.
The Lambda 2 PC-controlled UV/ Vis spectrometers are designed for routine and automated analyses. They offer total flexibility in method definition, double beam optics for long-term stability, basic methods for Scan, Timedrive, Wavelength Pro-New products The APL*Plus II Developer's Kit, which comprises both the APL*Plus II application development system and a runtime system, allows unlimited usage of the runtime system, giving developers the ability to distribute an unlimited number of APLbased applications to as many applications sites as needed for the price of about five full systems. A Conversion Kit is available for developers who are already using the APL*Plus II system and just want a runtime licence to distribute their applications. Index Instruments has launched a more accurate general-purpose refractometer. The refractometer reads to 0.00005 Refractive Index Units (RI) or 0.05% sugar content (BRIX). The GPR11-37X is ideal for factory and quality control applications in many areas, for example sugar reofining, the food industry, pharmaceuticals, chemicals and adhesives manufacture. Many of these are 'dirty' applications where the ability to douse the equipment with water during cleaning is of particular beneofit. Readings are displayed on a 48-character LCD readout. There are also dual RS232 outputs for connection to a digital printer or computer. The GPR11-37X accommodates the full range of Index Instruments refractometer cells for bench orjTow-through (on-line) .process analysis.

Ultrasonic homogenizers
In order to facilitate such processes as microdisruption, emulsification and the production ofsuspension, the Biotechnology Division of B. Braun Medical Ltd has introduced the Labsonic series of competitively-priced ultrasonic homogenizers.
All Labsonic models have an output frequency of 20kH and have built-in timers for homogenization periods of between 0 and 15 min and various power outputs are available. For example, the Labsonic U is rated at over 340W, while the budget-priced labsonic L has an output in excess of 200W. B. Braun also supplies a comprehensive range of accessories for its homogenizers.
Labsonic homogenizers utilize a piezo-electric transducer in the probe assembly, which produces an extremely-high accoustic pressure within the process fluid, thereby Development of 386-based applications STSC International has expanded its range of APL programming products with the APL*Plus II Runtime Developer's Kit, which enables developers to expand their user base at no additional cost. APL*Plus II is a complete second generation APL system and powerful application development tool. It is specifically designed for software applications which unleash the true power and capacity of 386-based PCs. The APL*Plus II system is particularly well-suited for applications designed to solve complex numeric problems because of its exceptional handling of tables and multi-dimensional arrays. APL's concise code enables developers to work much more productively--up to 10 times faster than with conventional programming languages like C, Fortran and Pascal. APL*Plus II has no limit on the application workspace size up to the limit of the available memory. It is, for example, possible to have a 15Mbyte workspace in a machine with only 16Mbytes of RAM. There is also no limit on variable size up to the size of the workspace and no performance penalty for using large arrays. Mainframe data types such as 32-bit integers and 1-bit Booleans are also supported. In addition, the APL session manager is fully integrated with the full-screen editor. Centrifugal concentration and freeze drying Genevac have introduced a combined centrifugal concentrator and freeze dryer--the SF50. Combined with the Cole vacuum pump--the CVP 100, Genevac are able to offer an effective evaporation and freeze-drying system which operates without the need for chemical or cold traps. This two-in-one laboratory evaporation system achieves rapid removal of aqueous or volatile organic solvents, acids and bases to dry or concentrate samples.
There are three versions of the SF50. The basic version has a heating and spin facility. The gauge version provides a bar graph display giving readings of vacuum pressure at the rotor chamber. The 'Vac-Stop' version includes a vacuum gauge and a controller. This allows the SF50 to be operated in a Vac-Stop mode in which the system shuts down automatically when the required level of dryness is reached.
A variety of rotors are available for the SF50 alternatively Genevac can provide custom rotors. A choice of three chambers are also available-standard acrylic, ported lyophilizer chamber with four ports able to accommodate four 250 ml flasks or safety borosilicate glass.
The chamber base plate and internal tubing are stainless steel for corrosion resistance and easy cleaning. No bearings are exposed to corrosives in the sample chamber. Details from Amanda Kerr, Genevac Ltd, 9 Farthing Road, Sproughton, Ipswich IP1 5AP, UK. Tel.: 0473 240000.

Built-in liquid autosampler
The AutoSystem Gas Chromato graph from Perkin-Elmer features a built-in 82-position autosampler, providing a cost-effective, spaceefficient and completely automated instrument. The sampling tower rotates on an arc to access two injector ports, while allowing unobstructed access to the injection ports without removal of the autosampler.
Parameters for two separate automation modes can be programmed through the system keyboard, offering the ability to perform individual runs with different columns and conditions. The three AutoSystem speeds of injection and five GC methods are also programmed through the keyboard.