My coeditors and I are delighted to share this special issue of the Journal of Obesity focused on understanding the comorbidity between obesity and depression. Depression is highly comorbid with obesity [
Obesity in childhood is highly predictive of adult obesity [
In adults, the positive association observed between depression and obesity is relatively robust, though the relationship between suicidal ideation and obesity, particularly in women, is less clear. G. Zhao and colleagues used NHANES data to examine the relationship between suicide and obesity, waist-hip ratio, and waist circumference. Though depression may not necessarily hinder weight loss treatment [
The fact that negative moods can both prompt and result from binge eating episodes, and that binge eating is associated with obesity, suggests that a conversation about depression and obesity would be remiss if it did not include binge eating. R. F. Petersen and colleagues examined the relationship between binge eating disorder, depression, anxiety, and caloric intake in overweight and obese adult women to elucidate how negative mood states impact food intake in the context of binge eating disorder. The work of J. W. Jahng and colleagues provides additional insight into why negative moods may result in binge eating by exploring the dopaminergic activity of rats during fasting and refeeding cycles. These papers nicely set the stage for the study by C. Cifani and colleagues who explored a potential treatment agent for binge eating,
Lastly, as physical activity may serve as a protective factor for obesity and depression, it is important to understand the barriers and facilitators to engagement in physical activity. W. Yang and colleagues explore some of the individual and environmental variables that are associated with engagement in leisure time physical activity. These factors may serve as important treatment targets for interventions that seek to increase physical activity as a potentially parsimonious treatment for comorbid obesity and depression.
Although the articles in this special issue address a range of topics relevant to the depression and obesity comorbidity, there is clearly much more work to be done to reduce the comorbidity. We hope that this special issue stimulates ideas for future research and facilitates interventions for prevention and treatment.