Journal of Ophthalmology
Volume 2016 (2016), Article ID 1925683, 2 pages
http://dx.doi.org/10.1155/2016/1925683

Letter to the Editor

Response to: Comment on “The Effects of Hemodialysis on Tear Osmolarity”

Muhittin Taskapili,¹ Kubra Serefoglu Cabuk,² Rukiye Aydin,³ Kursat Atalay,² Ahmet Kirgiz,² Dede Sit,⁴ and Hasan Kayabasi⁴

¹Prof. Dr. N. Resat Belger Beyoglu Eye Training and Research Hospital, 34421 Istanbul, Turkey
²Bagcilar Training and Research Hospital, Ophthalmology Department, 34200 Istanbul, Turkey
³Ophthalmology Department, Medipol University, 34214 Istanbul, Turkey
⁴Bagcilar Training and Research Hospital, Nephrology Department, 34200 Istanbul, Turkey

Received 25 April 2016; Accepted 23 June 2016

Academic Editor: Biju B. Thomas

Copyright © 2016 Muhittin Taskapili et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

We thank Onder Ayyildiz and Gokhan Ozge for their interest and comment on our paper “The Effects of Hemodialysis on Tear Osmolarity” [1, 2]. They thought that detection of TO would be performed at the same time of the day regarding the duration of hemodialysis (HD) which may avoid the bias of the methodology according to the study of Niimi et al. [3].

Niimi et al. have enrolled 38 medically healthy neophytes. Their subjects reported to the CRC an average of hours (7–17 hours) after awakening for baseline measurements and sleeping at the CRC, thereby allowing for uniform environmental exposure (e.g., humidity and temperature) and timely collection of measurements upon awakening.

The physical conditions of our clinic are not suitable for all HD patients to report 7 hours after awakening for baseline measurements and sleeping one day thereby allowing for uniform environmental exposure (e.g., humidity and temperature) and timely collection of measurements upon awakening.

In our Hemodialysis Unit, two HD sessions have been performed; the first session was between 8:30 and 12:30 and the second session was between 13:00 and 17:00. 23 patients were in the first session and 20 patients were in the second session in our study. Tear osmolarity (TO) measurements have been performed one minute before the beginning of HD and 30 minutes after the termination of HD. There was no statistically significant difference between pre-HD tear TO measurements and between post-HD TO measurements of these two sessions (Table 1).

Table 1: Pre-HD and post-HD tear osmolarity according to HD sessions.

First session
Second session

Pre-HD tear osmolarity
312.2 ± 16.6
315.6 ± 18.9
0.528

Post-HD tear osmolarity
301.6 ± 18.3
302.1 ± 12.3
0.929

Statistical method: Student’s -test independent.

Competing Interests

None of the authors of this paper has a financial or personal relationship with other people or organisations that could inappropriately influence or bias the results.

References

O. Ayyildiz and G. Ozge, “Comment on ‘the effects of hemodialysis on tear osmolarity’,” Journal of Ophthalmology, vol. 2016, Article ID 6890685, 1 pages, 2016.

M. Taskapili, K. Serefoglu Cabuk, R. Aydin et al., “The effects of hemodialysis on tear osmolarity,” Journal of Ophthalmology, vol. 2015, Article ID 170361, 5 pages, 2015.

J. Niimi, B. Tan, J. Chang et al., “Diurnal pattern of tear osmolarity and its relationship to corneal thickness and deswelling,” Cornea, vol. 32, no. 10, pp. 1305–1310, 2013.