BioMed Research International
Volume 2021 (2021), Article ID 5516257, 10 pages
https://doi.org/10.1155/2021/5516257

Research Article

Does Birth Interval Matter in Under-Five Mortality? Evidence from Demographic and Health Surveys from Eight Countries in West Africa

Eugene Budu,¹ Bright Opoku Ahinkorah,² Edward Kwabena Ameyaw,² Abdul-Aziz Seidu,1,3 Betregiorgis Zegeye,⁴ and Sanni Yaya⁵

¹Department of Population and Health, University of Cape Coast, Cape Coast, Ghana
²School of Public Health, Faculty of Health, University of Technology Sydney, Ultimo, Australia
³College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Queensland, Australia
⁴HaSET Maternal and Child Health Research Program, Shewarobit Field Office, Shewa Robit, Ethiopia
⁵Faculty of Medicine, University of Parakou, Parakou, Benin

Correspondence should be addressed to Sanni Yaya; sanni.yaya@gmail.com

Received 31 January 2021; Accepted 8 May 2021; Published 17 May 2021

Academic Editor: Mihajlo Jakovljevic

Copyright © 2021 Eugene Budu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract.

In sub-Saharan Africa (SSA), every 1 in 12 children under five dies every year compared with 1 in 147 children in the high-income regions. Studies have shown an association between birth intervals and pregnancy outcomes such as low birth weight, preterm birth, and intrauterine growth restriction. In this study, we examined the association between birth interval and under-five mortality in eight countries in West Africa. A secondary analysis of the Demographic and Health Survey (DHS) data from eight West African countries was carried out. The sample size for this study comprised 52,877 childbearing women (15-49 years). A bivariate logistic regression analysis was carried out and the results were presented as crude odds ratio (cOR) and adjusted odds ratios (aOR) at 95% confidence interval (CI). Birth interval had a statistically significant independent association with under-five mortality, with children born to mothers who had >2 years birth interval less likely to die before their fifth birthday compared to mothers with ≤2 years birth interval [; ], and this persisted after controlling for the covariates [; ]. The country-specific results showed that children born to mothers who had >2 years birth interval were less likely to die before the age of five compared to mothers with ≤2 years birth interval in all the eight countries. In terms of the covariates, wealth quintile, mother’s age, mother’s age at first birth, partner’s age, employment status, current pregnancy intention, sex of child, size of child at birth, birth order, type of birth, and contraceptive use also had associations with under-five mortality. We conclude that shorter birth intervals are associated with higher under-five mortality. Other maternal and child characteristics also have associations with under-five mortality. Reproductive health interventions aimed at reducing under-five mortality should focus on lengthening birth intervals. Such interventions should be implemented, taking into consideration the characteristics of women and their children.

1. Introduction

Under-five mortality is a global indicator of the overall development children’s health, and nations’ socioeconomic and environmental conditions for both children, household, and community [1]. To deal with this, the United Nations in 2000 signed the Millennial Development Goals, which included the reduction of child mortality and improving maternal health by 2015 [2]. Western Africa is known to have the world’s highest MMR rates and one of the highest rates for under-five mortality in children, including at the neonatal stage [3]. Although under-five mortality has reduced significantly, it remains a major health challenge in both low- and middle-income countries (LMICs). SSA, which is the home of most LMICs, has in the last two decades witnessed a decline in under-five mortality. However, it is still the home of persistently high rates of under-five mortality compared with high-income countries (HICs) [4, 5]. This has led to the target 2 of Sustainable Development Goal (SDG) 3 which aims to reduce under-five mortality to at least 25 per 1000 live births by 2030 [6].

In SSA, every 1 in 12 children under five years dies every year compared with 1 in 147 children in the HICs [7]. The high under-five mortality in SSA can be avoided with improved coverage of immunization, prevention, early treatment, and control of malaria and diarrhea as well as other prevalent childhood diseases [8]. Notable measures have been put in place to reduce under-five mortality through strengthening healthcare systems, increasing the supply of primary healthcare facilities and services to the local community [9].

However, literature has shown that in LMICs, education, household size, and age of women are essential determinants of under-five mortality [10]. For instance, education has been found to improve the knowledge and skills of the mother to effectively access, understand, and utilize information and resources which are helpful for child health and overall development [11]. Large family size can also expose children to a high risk of death due to constraints on family finances, while early and late maternal age has been found to increase the risk of under-five mortality due to less use of maternal and child healthcare services attributed to the barriers to healthcare access [11]. Apart from these factors, studies have also shown that the time between a previous live birth and index live birth may have adverse outcomes including under-five mortality, low birth weight, preterm birth, and intrauterine growth restriction [12]. This is because a woman may not have physiologically recovered from the previous birth if she conceives the next child in less than 36 months [12]. Birth interval, therefore, plays a major role in child mortality and the World Health Organization recommends that women space their births at least three years and at most five years to reduce maternal and child health risks [13]. Short birth spacing whether intended or otherwise will have negative outcomes on the physiologic and anatomic capacity of the woman [12]. This is because intervals less than three years could be associated with an elevated risk of infant death or injury [14]. In West Africa, under-five mortality rates are more than twice the rate for most countries in other parts of the continent [13]. However, studies on under-five mortality in West Africa have focused so much attention on the demographic and socioeconomic factors associated with under-five mortality. There is therefore a dearth of evidence on the association between birth interval and under-five mortality in West Africa [15–18]. Hence, this study examined the association between birth interval and under-five mortality in eight countries in West Africa.

2. Methods and Materials

2.1. Study Design and Data Source

A secondary analysis of the Demographic and Health Survey (DHS) data on women in West Africa was done from eight West African countries in Burkina Faso (2010), Benin (2018-2018), Cote D’Ivorie (2011-2012), Gambia (2013), Mali (2018), Nigeria (2018), Sierra Leone (2019), and Togo (2013-2014). The DHS is a nationally representative survey designed to collect data on various health topics such as nutrition, mortality, domestic violence, and female genital mutilation, access to mass media, fertility, young child development, breastfeeding and food intake, vaccinations, and treatment of diseases. A stratified dual-stage sampling approach was employed, and the same questions were posed to women of all these countries and thus make it feasible for multicountry study. The study involved a multistage sampling process (i.e., enumeration areas [EAs]), followed by systematic household sampling within the selected EAs. The sample size for this study comprised 52,877 childbearing women (see Table 1) between the ages of 15-49. We followed the “Strengthening the Reporting of Observational Studies in Epidemiology” (STROBE) guidelines in conducting this study. The data set is freely available to the public at https://dhsprogram.com/data/available-datasets.cfm.

Table 1: Sample.

Country
Year
Weighted ()
Weighted (%)
Under-five mortality rate (per 1000 live births)

Benin
2017/2018
7680
14.52
72

Burkina Faso
2010
9580
18.12
94

Cote D’Ivorie
2011-12
3489
6.60
72

Gambia
2013
4183
7.91
36

Mali
2018
5463
10.33
69

Nigeria
2018
13234
25.03
96

Sierra Leone
2019
5374
10.16
100

Togo
2013-14
3873
7.33
57

Total
—
52877
100
74

2.2. Definition of Variables

2.2.1. Outcome Variables

The study used under-five mortality as the outcome variable. Under-five mortality, also known as child mortality, refers to the death of infants and children under the age of five. This variable took a binary form; such that under-five mortality will be regarded as a success (1 = if death occurs in the specified age period) or failure (0 = if the child is alive in the specified age period).

2.2.2. Independent Variable

The study used birth interval as the main independent variable. This was derived from asking the women the time preceding birth interval. Responses to this were stated in months. For the purpose of this study, this variable was categorised into 1 = less or equal to 2 years and 2 = more than 2 years.

2.2.3. Control Variables

Twenty-one (21) control variables were considered for our study. These variables were made up of maternal factors, child factors, and contextual factors. The maternal factors were mother’s age, mother’s age at birth, husband/partner’s age, mother’s religion, mother’s educational level, mother’s employment status, father’s employment status, sexual autonomy, contraceptive use, mother’s experience of IPV, mother’s exposure to mass media, and desire for pregnancy. The child factors were the sex of the child, size of the child at birth, birth order, the type of delivery, delivery assistance, place of delivery, and antenatal care. Place of residence, wealth quintile, and country were the contextual factors. These variables were not determined a priori; instead, based on parsimony, theoretical relevance, and practical significance with under-five mortality [15–18].

2.3. Statistical Analyses

Analysis for the study was done using Stata version 16.0. Univariate, bivariate, and multilevel and binary logistic regression analyses were conducted. Frequencies and proportions were first conducted, followed by a distribution of under-five mortality per the explanatory variables considered in this study, with their respective confidence intervals (CIs). After this, we carried out a multilevel logistic regression analysis to examine the factors associated with under-five mortality using five models. Model 0 showed the variance in under-five mortality attributed to the clustering of the primary sampling units (PSUs) without the explanatory variables. Model 1 contained the main independent variable (birth interval) and under-five mortality. Model 2 and 3 contained the child and maternal factors, respectively, and under-five mortality, while Model 4 contained the contextual factors. Model 5 contained all the independent and control variables. The Stata command “melogit” was used in fitting these models. We used Akaike’s Information Criterion (AIC) tests for model comparison. Finally, we stratified our analysis by country to examine the heterogeneity in under-five mortality in all countries using binary logistic regression. Statistical significance was considered at a value less than 0.05 and odds ratios at 95 percent confidence intervals were determined. This was followed by a multivariable binary logistic regression. Statistical significance was considered at a value less than 0.05 and odds ratios at 95 percent confidence intervals were determined. All frequency distributions were weighted, while the survey command (SVY) in Stata was used to adjust for the complex sampling structure of the data in the regression analyses.

3. Results

3.1. Characteristics of Respondents and Under-Five Mortality Rate in West Africa

Table 2 shows the distribution of under-five mortality across birth interval and other characteristics of women. The highest under-five mortality rate was found among mothers with ≤2 years (108 deaths per 1000 live births), those in rural areas (85 deaths per 1000 live births), those with the poorest wealth quintile (95 deaths per 1000 live births), mothers aged <20 years (108 deaths per 1000 live births), mothers whose age at first childbirth were <20 years (84 deaths per 1000 live births), and women whose partners were 50+ years (94 deaths per 1000 live births). Muslim women (82 deaths per 1000 live births), women with no formal education (88 deaths per 1000 live births), employed women (77 deaths per 1000 live births), women whose partners were employed (75 deaths per 1000 live births), those who were not exposed to media (82 deaths per 1000 live births), and those whose pregnancies were intended (77 deaths per 1000 live births) had the highest under-five mortality rates. Disparities in under-five mortality rate were also found among the sex of children, size of child at birth, birth order, sexual autonomy, type of birth, place of delivery, delivery assistance, ANC attendance, mother’s experience of IPV, and contraceptive use.

Table 2: Characteristics of respondents and under-five mortality rate in West Africa.

Variables
Weighted
Weighted %
Under-five mortality

Birth interval

    ≤2 years
7681
14.5
108 [96-120]

    >2 years
45196
85.5
68 [63-73]

Place of residence

    Urban
18096
34.2
56 [50-61]

    Rural
34780
65.8
85 [77-94]

Wealth quintile

    Poorest
10700
20.2
95 [81-106]

    Poorer
11067
20.9
93 [80-105]

    Middle
11009
20.8
75 [66-84]

    Richer
10541
19.9
71 [61-80]

    Richest
9560
18.1
40 [33-47]

Mother’s age

    <20 years
2705
5.1
108 [80-136]

    20-29 years
24461
46.3
67 [60-74]

    30-49 years
25711
48.6
77 [72-82]

Mother’s age at first birth

    <20 years
30572
57.8
84 [78-90]

    20-29 years
21136
40.0
63 [55-70]

    30-49 years
1169
2.2
47 [31-62]

Partner’s age

    <30 years
7746
14.7
78 [60-95]

    30-39 years
20743
39.2
62 [57-68]

    40-49 years
15802
29.9
74 [66-82]

    50+ years
8586
16.2
94 [85-103]

Religion

    Christian
13881
26.2
62 [55-69]

    Islam
31390
59.4
82 [75-89]

    Others
7606
14.4
69 [57-80]

Educational level

    No education
31565
59.7
88 [80-96]

    Primary
8895
16.8
69 [60-78]

    Secondary
10423
19.7
47 [40-53]

    Higher
1993
3.8
39 [30-48]

Employment status

    Unemployed
9150
17.3
62 [51-73]

    Employed
43727
82.7
77 [72-82]

Partner’s employment status

    Unemployed
1092
2.1
44 [27-61]

    Employed
51785
97.9
75 [71-80]

Exposure to mass media

    Not exposed
17382
32.9
82 [75-90]

    Exposed
35.495
67.1
71 [66-76]

Current pregnancy intended

    Then
39061
743.8
79 [73-85]

    Later
3130
5.9
66 [53-79]

    No more
10730
20.3
63 [54-72]

Sex of child

    Male
26958
51.0
81 [75-87]

    Female
25919
49.0
68 [62-74]

Size of child at birth

    Very large
6538
12.4
63 [51-76]

    Larger than average
12732
24.1
66 [56-75]

    Average
26054
49.3
75 [69-81]

    Smaller than average
5626
10.6
94 [80-109]

    Very small
1927
3.6
114 [91-138]

Birth order

    First
8414
15.9
71 [62-79]

    2-3
18353
34.7
53 [48-60]

    4 or more
26110
49.4
88 [82-95]

Sexual autonomy

    No
11263
21.3
82 [69-95]

    Yes
41614
78.7
72 [68-77]

Type of birth

    Virginal birth
50896
96.3
74 [69-79]

    Caesarean birth
1981
3.7
90 [65-114]

Place of delivery

    Home
17035
32.2
103 [92-113]

    Health facility
35842
67.8
61 [56-66]

Delivery assistance

    TBA/others
12335
23.3
107 [94-121]

    SBA/health professionals
40542
76.7
65 [59-70]

ANC attendance

    No
22487
42.5
89 [82-96]

    Yes
30390
57.5
65 [59-70]

Mother experience IPV

    No
43965
83.1
74 [69-79]

    Yes
8912
16.9
77 [63-91]

Contraceptive use

    No
42958
81.2
84 [76-91]

    Yes
9919
18.8
42 [35-49]

3.2. Association between Birth Interval and Under-Five Mortality

As shown in Table 3, the birth interval had a significant independent association with under-five mortality, with children born to mothers who had >2 years birth interval less likely to die before the age of five compared to mothers with ≤2 years birth interval [; ], and this persisted after controlling for the covariates [; ]. In terms of the covariates, children born to women aged 20-29 years [; ] were less likely to die before 5 years compared to those aged <20 years while children born to women whose partners were 50+ years were more likely to die compared to those whose partners were aged 15-19 [; ]. Children whose mothers were employed were more likely to die before age five compared to those born to unemployed mothers [; ]. Children whose mothers were exposed to mass media were more likely to die compared to those whose mothers were not exposed [; ]. Children whose mothers’ current pregnancy was intended were more likely to die before age five compared to those whose mothers’ current pregnancy was unintended. Women who were using contraceptives at the time of the survey were less likely to have experienced under-five mortality compared to those who were not using contraceptives [; ]. The odds of under-five mortality were lower among female children and 2-3 birth order children but higher among very small children, compared to male children, first birth order children, and very large children. Children born to mothers with the richest wealth quintile were less likely to die before age five compared to those born to the poorest mothers [; ]. Finally, compared to Burkina Faso, the death of children under five was lower in Benin, Gambia, Mali, and Togo but higher in Sierra Leone (Table 3).

Table 3: Multilevel regression analysis of the association between under-five mortality in West Africa and sociodemographic and behavioral characteristics.

Variables
Model 0
Model 1
cOR (95% CI)
Model 2
aOR (95% CI)
Model 3
aOR (95% CI)
Model 4
aOR (95% CI)
Model 5
aOR (95% CI)

Birth interval

    ≤2 years

Ref

Ref

    >2 years

0.56 (0.51-0.62)

0.55 (0.50-0.61)

Mother’s age

    <20 years

Ref

Ref

    20-29 years

0.73 (0.61-0.88)

0.74 (0.60-0.90)

    30-49 years

0.96 (0.78-1.18)

0.88 (0.69-1.13)

Mother’s age at first birth

    <20 years

Ref

Ref

    20-29 years

0.86 (0.78-0.94)

0.93 (0.84-1.02)

    30-49 years

0.74 (0.54-1.01)

0.78 (0.57-1.09)

Partner’s age

    <30 years

Ref

Ref

    30-39 years

0.88 (0.77-1.01)

0.88 (0.76-1.02)

    40-49 years

1.01 (0.86-1.18)

0.99 (0.84-1.17)

    50+ years

1.25 (1.05-1.48)

1.23 (1.03-1.47)

Religion

    Christian

Ref

Ref

    Islam

1.05 (0.95-1.17)

1.09 (0.97-1.22)

    Others

0.92 (0.80-1.06)

1.04 (0.86-1.25)

Educational level

    No education

Ref

Ref

    Primary

0.97 (0.87-1.09)

1.02 (0.90-1.15)

    Secondary

0.85 (0.75-0.96)

0.88 (0.77-1.02)

    Higher

0.76 (0.57-1.00)

0.81 (0.60-1.10)

Employment status

    Unemployed

Ref

Ref

    Employed

1.39 (1.23-1.57)

1.16 (1.02-1.33)

Partner’s employment status

    Unemployed

Ref

Ref

    Employed

1.20 (0.86-1.66)

1.28 (0.92-1.77)

Sexual autonomy

    No

Ref

Ref

    Yes

1.05 (0.95-1.16)

0.99 (0.89-1.11)

Exposure to mass media

    Not exposed

Ref

Ref

    Exposed

0.95 (0.88-1.04)

1.12 (1.02-1.23)

Current pregnancy intended

    Then

Ref

Ref

    Later

0.81 (0.68-0.98)

0.75 (0.62-0.90)

    No more

0.75 (0.66-0.84)

0.70 (0.62-0.79)

Mother experience IPV

    No

Ref

Ref

    Yes

1.10 (0.99-1.22)

1.08 (0.97-1.21)

Contraceptive use

    No

Ref

Ref

    Yes

0.69 (0.61-0.78)

0.70 (0.62-0.79)

Sex of child

    Male

Ref

Ref

    Female

0.82 (0.76-0.89)

0.83 (0.76-0.90)

Size of child at birth

    Very large

Ref

Ref

    Larger than average

0.92 (0.79-1.06)

0.89 (0.77-1.04)

    Average

1.03 (0.90-1.17)

0.96 (0.84-1.10)

    Smaller than average

1.29 (1.09-1.52)

1.24 (1.05-1.47)

    Very small

2.01 (1.65-2.44)

2.07 (1.70-2.53)

Birth order

    First

Ref

    2-3

0.79 (0.69-0.90)

0.72 (0.62-0.84)

    4 or more

1.22 (1.09-1.38)

1.02 (0.86-1.23)

Type of birth

    Virginal birth

Ref

Ref

    Caesarean birth

1.81 (1.50-2.18)

ANC attendance

    No

Ref

Ref

    Yes

0.90 (0.83-0.98)

0.96 (0.87-1.05)

Place of delivery

    Home

Ref

Ref

    Health facility

0.77 (0.68-0.87)

0.97 (0.85-1.11)

Delivery assistance

    TBA/others

Ref

Ref

    SBA/health professionals

0.99 (0.87-1.12)

0.91 (0.79-1.03)

Place of residence

    Urban

Ref
Ref

    Rural

1.04 (0.93-1.16)
1.01 (0.90-1.14)

Wealth quintile

    Poorest

Ref
Ref

    Poorer

0.97 (0.87-1.09)
1.04 (0.92-1.17)

    Middle

0.86 (0.76-0.97)
0.96 (0.85-1.09)

    Richer

0.83 (0.73-0.95)
1.00 (0.87-1.16)

    Richest

0.53 (0.45-0.63)
0.72 (0.59-0.87)

Country

    Burkina Faso

Ref
Ref

    Benin

0.77 (0.66-0.89)
0.81 (0.69-0.96)

    Cote d’Ivorie

1.03 (0.86-1.22)
1.07 (0.89-1.29)

    Gambia

0.44 (0.36-0.55)
0.39 (0.30-0.49)

    Mali

0.82 (0.70-0.55)
0.77 (0.64-0.92)

    Nigeria

1.16 (1.03-1.30)
1.14 (0.99-1.32)

    Sierra Leone

1.13 (0.97-1.31)
1.30 (1.10-1.55)

    Togo

0.70 (0.58-0.85)
0.78 (0.61-1.00)

Random effect result

    PSU variance (95% CI)
0.07 (0.04-0.13)
0.07 (0.04-0.13)
0.06 (0.03-0.12)
0.06 (0.03-0.12)
0.05 (0.02-1.00)
0.04 (0.02-0.10)

    ICC
0.0211678
0.0207558
0.0180652
0.0185152
0.0139181
0.0132386

    LR test
15.92 ()
15.37 ()
12.03 ()
12.46 ()
7.51 ()
6.74 ()

    Wald chi-square

131.30
233.56
282.90
209.09
721.41

    Model fitness

    Log-likelihood
-10031.127
-99714453
-9909.8115
-9893.1726
-9915.005
-9661.2923

    AIC
20066.25
19948.89
19863.62
19812.35
19858.01
19414.58

    N
52877
52877
52877
52877
52877
52877

, , .

The country-specific results showed that children born to mothers who had >2 years birth interval were less likely to die before the age of five compared to mothers with ≤2 years birth interval in all the eight countries (Table 4).

Table 4: Binary regression analysis of the association birth interval and under-five mortality in West Africa disaggregated by county.

Country
Model 1
cOR (95% CI)
Model 2
aOR (95% CI)

Benin
0.51 (0.39-0.65)
0.52 (0.40-0.67)

Burkina Faso
0.68 (0.50-0.91)
0.64 (0.47-0.89)

Cote d’Ivorie
0.53 (0.36-0.76)
0.55 (0.37-0.82)

Gambia
0.58 (0.35-0.96)
0.47 (0.27-0.82)

Mali
0.63 (0.46-0.86)
0.63 (0.45-0.88)

Nigeria
0.67 (0.56-0.79)
0.65 (0.54-0.76)

Sierra Leone
0.39 (0.30-0.51)
0.38 (0.29-0.51)

Togo
0.44 (0.29-0.67)
0.37 (0.24-0.58)

4. Discussion

The focus of this study was to assess the association between birth interval and under-five mortality in eight West African countries, using data from the DHS. From the study, the odds of children dying before age 5 was higher among children born to mothers who had more than a 2-year space between the previous birth compared to children born to mothers who had less or equal to 2 years interval. This confirms previous studies on the association between birth interval and under-five mortality [19] such as other low- and middle-income countries such as Kenya [20], South Africa [21], and Bangladesh [22]. A possible explanation for this is that mothers that waited for more than 18 months before having the next baby would have regained most body nutrients and blood loss during previous pregnancy and breastfeeding. It is also a common medical knowledge that the risk of obstetrics complications is higher in mothers that had a short birth interval than those with long birth interval.

Children from the richest households, those whose mothers age were 20-29, those whose mothers gave birth by age 20-29, and those whose mothers said their current pregnancy were mistimed and unwanted had a lower risk of under-five mortality. On the contrary, children whose fathers were 50 years and above, whose size at birth were smaller than average and very small, and those whose mothers had caesarean section have a higher risk of under-five mortality. These findings are consistent with previous reports [23–28]. From this study, it was seen that children of women who are employed were more likely to die before their 5th birthday. This finding contradicts the finding of previous studies [27–29].

The study further established that under-five mortality varied by child sex, with female children having smaller odds of dying before their 5th birthday, compared to male children. Several studies confirm this finding [8, 30–32]. Two explanations can be drawn from this finding. This explanation can be seen as biological and social. Biologically, male children who are susceptible to infection, more likely to be born premature, have a larger average body size and big head circumference which extend the time for mothers giving birth to male children [8, 31, 33]. Socially, gender discrimination in relation to feeding and medical care practices exists among male and female children, with the practices favoring females [8, 31, 33]. From this study, it was seen that children with a birth order of 2-3 were less likely to die before their 5th birthday compared to children who are firstborns. This finding contradicts the findings of previous studies which state that the higher birth orders the higher the likelihood of under-five mortality [34]. The findings of the study also established that there is an association between contraceptive use and under-five mortality. The likelihood of under-five mortality reduced in children of mothers that embraced the use of contraception.

4.1. Strengths and Limitations

Our study’s strength lies in the use of nationally representative datasets from eight countries in West Africa under the DHS program. This fortifies the generalizability of our study findings to the general population of young women. Moreover, the use of binary logistics regression and a large sample size ensured the reliability and replicability of the study to other populations. Notwithstanding the apparent strengths of our study, we caution that our findings be interpreted in the light of some limitations. Given that the dataset used employed cross-sectional designs, it limits the possibility of causal inferences primarily because of the snapshot nature of such design. The data used in this study is a retrospective self-reporting data, and as such, it may be biased by the mother’s perception or feeling about pregnancy which might change over time.

5. Conclusion

We conclude that shorter birth intervals are associated with higher under-five mortality. Wealth quintile, mother’s age, mother’s age at first birth, partner’s age, employment status, current pregnancy intention, sex of child, size of child at birth, birth order, type of birth, and contraceptive use also had associations with under-five mortality. Reproductive health interventions aimed at reducing under-five mortality should focus on lengthening birth intervals. Such interventions should be implemented taking into consideration the characteristics of women and their children.

Abbreviations

AOR: | Adjusted odds ratio
CI: | Confidence interval
DHS: | Demographic and health survey
LMIC: | Low- and middle-income countries
SDGs: | Sustainable development goal
SSA: | Sub-Saharan Africa.

Data Availability

Data for this study were sourced from Demographic and Health surveys (DHS) and available here: http://dhsprogram.com/data/available-datasets.cfm.

Ethical Approval

The DHS reports that ethical clearances were obtained from the Ethics Committee of ORC Macro Inc. as well as Ethics Boards of partner organizations of the various countries such as the Ministries of Health. The DHS follows the standards for ensuring the protection of respondents’ privacy. Inner City Fund International ensures that the survey complies with the United States Department of Health and Human Services’ regulations for the respect of human subjects. Since this was a secondary analysis, no further ethical approval was required because the datasets are available for download in the public domain. Further information about the DHS data usage and ethical standards are available at http://goo.gl/ny8T6X.

Consent

No consent to publish was needed for this study as we did not use any details, images, or videos related to individual participants. In addition, data used are available in the public domain.

Conflicts of Interest

The authors declare that they have no conflicts of interest.

Authors’ Contributions

EB and SY contributed to the study design and conceptualization, reviewed the literature, and performed the analysis. BOA, EKA, AS, and BZ provided technical support and critically reviewed the manuscript for its intellectual content. SY had final responsibility to submit for publication. All authors read and amended drafts of the paper and approved the final version.

Acknowledgments

The authors thank the MEASURE DHS project for their support and for free access to the original data.

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