ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count hsa04933 AGE-RAGE signaling pathway in diabetic complications 5/5 100/8081 2.62492E-10 3.10E-08 8.57E-09 IL6/VEGFA/TNF/CASP3/MAPK8 5 hsa05133 Pertussis 4/5 76/8081 3.58718E-08 2.12E-06 5.85E-07 IL6/TNF/CASP3/MAPK8 4 hsa04657 IL-17 signaling pathway 4/5 94/8081 8.51105E-08 3.35E-06 9.26E-07 IL6/TNF/CASP3/MAPK8 4 hsa04668 TNF signaling pathway 4/5 112/8081 1.7303E-07 5.10E-06 1.41E-06 IL6/TNF/CASP3/MAPK8 4 hsa04932 Non-alcoholic fatty liver disease 4/5 150/8081 5.62293E-07 1.33E-05 3.67E-06 IL6/TNF/CASP3/MAPK8 4 hsa05161 Hepatitis B 4/5 162/8081 7.66372E-07 1.51E-05 4.17E-06 IL6/TNF/CASP3/MAPK8 4 hsa05152 Tuberculosis 4/5 180/8081 1.17034E-06 1.97E-05 5.46E-06 IL6/TNF/CASP3/MAPK8 4 hsa05167 Kaposi sarcoma-associated herpesvirus infection 4/5 193/8081 1.54836E-06 2.19E-05 6.07E-06 IL6/VEGFA/CASP3/MAPK8 4 hsa05130 Pathogenic Escherichia coli infection 4/5 197/8081 1.68116E-06 2.19E-05 6.07E-06 IL6/TNF/CASP3/MAPK8 4 hsa05169 Epstein-Barr virus infection 4/5 202/8081 1.85892E-06 2.19E-05 6.07E-06 IL6/TNF/CASP3/MAPK8 4 hsa05163 Human cytomegalovirus infection 4/5 225/8081 2.86357E-06 3.07E-05 8.49E-06 IL6/VEGFA/TNF/CASP3 4 hsa05134 Legionellosis 3/5 57/8081 3.29478E-06 3.24E-05 8.96E-06 IL6/TNF/CASP3 3 hsa05132 Salmonella infection 4/5 249/8081 4.29582E-06 3.90E-05 1.08E-05 IL6/TNF/CASP3/MAPK8 4 hsa05020 Prion disease 4/5 273/8081 6.20538E-06 5.23E-05 1.45E-05 IL6/TNF/CASP3/MAPK8 4 hsa04010 MAPK signaling pathway 4/5 294/8081 8.34191E-06 6.56E-05 1.81E-05 VEGFA/TNF/CASP3/MAPK8 4 hsa05323 Rheumatoid arthritis 3/5 93/8081 1.45141E-05 0.000107042 2.96E-05 IL6/VEGFA/TNF 3 hsa05142 Chagas disease 3/5 102/8081 1.91721E-05 0.000115911 3.21E-05 IL6/TNF/MAPK8 3 hsa05146 Amoebiasis 3/5 102/8081 1.91721E-05 0.000115911 3.21E-05 IL6/TNF/CASP3 3 hsa04620 Toll-like receptor signaling pathway 3/5 104/8081 2.03262E-05 0.000115911 3.21E-05 IL6/TNF/MAPK8 3 hsa04625 C-type lectin receptor signaling pathway 3/5 104/8081 2.03262E-05 0.000115911 3.21E-05 IL6/TNF/MAPK8 3 hsa05010 Alzheimer disease 4/5 369/8081 2.06282E-05 0.000115911 3.21E-05 IL6/TNF/CASP3/MAPK8 4 hsa04931 Insulin resistance 3/5 108/8081 2.27705E-05 0.000122133 3.38E-05 IL6/TNF/MAPK8 3 hsa05145 Toxoplasmosis 3/5 112/8081 2.5402E-05 0.000130323 3.60E-05 TNF/CASP3/MAPK8 3 hsa04210 Apoptosis 3/5 136/8081 4.54941E-05 0.000212259 5.87E-05 TNF/CASP3/MAPK8 3 hsa05135 Yersinia infection 3/5 137/8081 4.65039E-05 0.000212259 5.87E-05 IL6/TNF/MAPK8 3 hsa05162 Measles 3/5 139/8081 4.85677E-05 0.000212259 5.87E-05 IL6/CASP3/MAPK8 3 hsa05418 Fluid shear stress and atherosclerosis 3/5 139/8081 4.85677E-05 0.000212259 5.87E-05 VEGFA/TNF/MAPK8 3 hsa05022 Pathways of neurodegeneration - multiple diseases 4/5 475/8081 5.62288E-05 0.000236964 6.55E-05 IL6/TNF/CASP3/MAPK8 4 hsa05164 Influenza A 3/5 171/8081 9.02504E-05 0.000367226 0.000101552 IL6/TNF/CASP3 3 hsa04621 NOD-like receptor signaling pathway 3/5 181/8081 0.000106931 0.000420595 0.000116311 IL6/TNF/MAPK8 3 hsa01523 Antifolate resistance 2/5 31/8081 0.000141412 0.000538277 0.000148854 IL6/TNF 2 hsa04215 Apoptosis - multiple species 2/5 32/8081 0.000150802 0.000554088 0.000153227 CASP3/MAPK8 2 hsa05205 Proteoglycans in cancer 3/5 205/8081 0.000154957 0.000554088 0.000153227 VEGFA/TNF/CASP3 3 hsa05170 Human immunodeficiency virus 1 infection 3/5 212/8081 0.000171235 0.000594288 0.000164344 TNF/CASP3/MAPK8 3 hsa05166 Human T-cell leukemia virus 1 infection 3/5 219/8081 0.0001886 0.000635851 0.000175837 IL6/TNF/MAPK8 3 hsa05143 African trypanosomiasis 2/5 37/8081 0.000202237 0.000662888 0.000183314 IL6/TNF 2 hsa05171 Coronavirus disease - COVID-19 3/5 232/8081 0.000223841 0.000713872 0.000197413 IL6/TNF/MAPK8 3 hsa05332 Graft-versus-host disease 2/5 42/8081 0.000261126 0.000810866 0.000224236 IL6/TNF 2 hsa04930 Type II diabetes mellitus 2/5 46/8081 0.000313586 0.000948798 0.00026238 TNF/MAPK8 2 hsa05144 Malaria 2/5 50/8081 0.000370784 0.001093813 0.000302482 IL6/TNF 2 hsa05321 Inflammatory bowel disease 2/5 65/8081 0.000627234 0.001799291 0.000497574 IL6/TNF 2 hsa05165 Human papillomavirus infection 3/5 331/8081 0.000640426 0.001799291 0.000497574 VEGFA/TNF/CASP3 3 hsa04664 Fc epsilon RI signaling pathway 2/5 68/8081 0.00068643 0.001865812 0.000515969 TNF/MAPK8 2 hsa04920 Adipocytokine signaling pathway 2/5 69/8081 0.000706745 0.001865812 0.000515969 TNF/MAPK8 2 hsa04622 RIG-I-like receptor signaling pathway 2/5 70/8081 0.000727351 0.001865812 0.000515969 TNF/MAPK8 2 hsa05120 Epithelial cell signaling in Helicobacter pylori infection 2/5 70/8081 0.000727351 0.001865812 0.000515969 CASP3/MAPK8 2 hsa05212 Pancreatic cancer 2/5 76/8081 0.000857084 0.002151829 0.000595064 VEGFA/MAPK8 2 hsa01521 EGFR tyrosine kinase inhibitor resistance 2/5 79/8081 0.000925862 0.002276078 0.000629424 IL6/VEGFA 2 hsa05210 Colorectal cancer 2/5 86/8081 0.001096442 0.002640411 0.000730176 CASP3/MAPK8 2 hsa05410 Hypertrophic cardiomyopathy 2/5 90/8081 0.001200241 0.002832568 0.000783315 IL6/TNF 2 hsa04640 Hematopoietic cell lineage 2/5 99/8081 0.00145052 0.003356106 0.000928094 IL6/TNF 2 hsa04061 Viral protein interaction with cytokine and cytokine receptor 2/5 100/8081 0.001479754 0.003357904 0.000928591 IL6/TNF 2 hsa04660 T cell receptor signaling pathway 2/5 104/8081 0.001599529 0.003561216 0.000984814 TNF/MAPK8 2 hsa04659 Th17 cell differentiation 2/5 107/8081 0.001692336 0.003698068 0.001022659 IL6/MAPK8 2 hsa04066 HIF-1 signaling pathway 2/5 109/8081 0.001755621 0.003766605 0.001041612 IL6/VEGFA 2 hsa04071 Sphingolipid signaling pathway 2/5 119/8081 0.002088944 0.004385716 0.001212821 TNF/MAPK8 2 hsa05168 Herpes simplex virus 1 infection 3/5 498/8081 0.002118524 0.004385716 0.001212821 IL6/TNF/CASP3 3 hsa04380 Osteoclast differentiation 2/5 128/8081 0.002412884 0.004886125 0.001351203 TNF/MAPK8 2 hsa04926 Relaxin signaling pathway 2/5 129/8081 0.002450271 0.004886125 0.001351203 VEGFA/MAPK8 2 hsa04068 FoxO signaling pathway 2/5 131/8081 0.002525878 0.004886125 0.001351203 IL6/MAPK8 2 hsa04650 Natural killer cell mediated cytotoxicity 2/5 131/8081 0.002525878 0.004886125 0.001351203 TNF/CASP3 2 hsa05160 Hepatitis C 2/5 157/8081 0.003609124 0.006868977 0.001899539 TNF/CASP3 2 hsa04217 Necroptosis 2/5 159/8081 0.00370011 0.006930364 0.001916515 TNF/MAPK8 2 hsa04510 Focal adhesion 2/5 201/8081 0.00585896 0.010802458 0.002987299 VEGFA/MAPK8 2 hsa04014 Ras signaling pathway 2/5 232/8081 0.007750269 0.01406972 0.003890824 VEGFA/MAPK8 2 hsa05131 Shigellosis 2/5 246/8081 0.008685414 0.015528467 0.004294224 TNF/MAPK8 2 hsa05012 Parkinson disease 2/5 249/8081 0.008892275 0.015661021 0.00433088 CASP3/MAPK8 2 hsa04060 Cytokine-cytokine receptor interaction 2/5 295/8081 0.01234531 0.021422744 0.00592422 IL6/TNF 2 hsa05016 Huntington disease 2/5 306/8081 0.013247965 0.022655941 0.006265247 CASP3/MAPK8 2 hsa05206 MicroRNAs in cancer 2/5 310/8081 0.013583441 0.0228978 0.00633213 VEGFA/CASP3 2 hsa04151 PI3K-Akt signaling pathway 2/5 354/8081 0.017524243 0.029124798 0.008054137 IL6/VEGFA 2 hsa05014 Amyotrophic lateral sclerosis 2/5 364/8081 0.018482901 0.030291421 0.008376753 TNF/CASP3 2 hsa05310 Asthma 1/5 31/8081 0.019038873 0.030775165 0.008510527 TNF 1 hsa05330 Allograft rejection 1/5 38/8081 0.023297567 0.037150174 0.010273465 TNF 1 hsa05219 Bladder cancer 1/5 41/8081 0.025118187 0.039519281 0.010928615 VEGFA 1 hsa04940 Type I diabetes mellitus 1/5 43/8081 0.026330425 0.04088145 0.011305307 TNF 1 hsa04672 Intestinal immune network for IgA production 1/5 49/8081 0.029959905 0.045912582 0.012696611 IL6 1