Construction of a Multimodal Neuroimaging Data Fusion System and Evaluation of Mental Fatigue Using Nonlinear Analysis

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Introduction
During the developmental process of neuroimaging technology, the single-modality neuroimaging technology was initially the most widely used technology. e fusion of multimodal neuroimaging technology and the integration of data information of different modalities have been initiated as the magnetic resonance imaging (MRI) technology matures [1][2][3]. As neuroimaging technology develops, researches on functional MRI (fMRI) and electroencephalogram (EEG) occupy the majority [4,5].
Zhang et al. proposed a time-varying network analysis method based on an adaptive directed transfer function, which was utilized to analyze and discuss the dynamic brain network model during epileptic seizures; the results showed that this time-varying network analysis could better indicate the pathogenesis of epilepsy than EEG and fMRI [6]. Yao et al. proposed that MRI and EEG had low sensitivity and specificity while diagnosing sporadic Creutzfeldt-Jakob disease (sCJD); in contrast, the sensitivity and specificity of real-time quaking-induced conversion (RT-QuIC) were above 95% while diagnosing the same disease [7]. Sharma et al. applied MRI and EEG technologies to analyze and discuss the symptoms of CJD [8].
erefore, the singlemodality neuroimaging technology, i.e., EEG and fMRI, are no longer applicable in the diagnosis and symptom analysis of many diseases.
To overcome the limitations of single-modality neuroimaging technology, scholars have researched and explored the integration of the two methods. Dhiman found in the discussion of the pathogenesis of hereditary epilepsy patients that the fusion of MRI and EEG technology would be an effective means of implementation [9]. Lu et al. proposed a method that could simultaneously record EEG and fMRI signals and convert the recorded signals into EEG-fMRI music through the Jansen-Rit neural network model, thereby realizing the organic fusion of EEG and fMRI neural imaging technologies [10]. In summary, for the data fusion of multimodal neuroimaging technologies, research results vary. Research on EEG-fMRI data fusion is the most extensive; however, research that simultaneously considers temporal and spatial dimensions is rare. e problem of mental fatigue becomes increasingly serious as market competition intensifies, and the pace of production and life accelerates. e aggravation of mental fatigue causes a series of problems, such as reduced work efficiency and traffic accidents [11]. erefore, the analysis of mental fatigue is necessary. e human brain is a complex nonlinear system. Being in a fatigued state for a long time will accelerate brain aging. EEG signal can reflect brain activities, making it widely accepted in mental fatigue evaluation. e evaluation of mental fatigue based on EEG signals includes linear and nonlinear indexes. e former is generated by EEG power ratio, while the latter includes complexity and relevant dimensions. However, traditional mental fatigue evaluation methods based on EEG signals cannot analyze the overall state of the human brain; also, it is difficult for them to reveal the connections between different brain regions. e brain function network uses mutual information to measure the connection of different regions. It can also analyze the weights in different periods, including the resting state and the task state, which overcomes the shortcomings of traditional methods [12]. Many researchers have explored mental fatigue evaluation. Foong et al. analyzed the efficacy of neuromotor therapy in promoting the rehabilitation system. ey found that the existence of EEG was correlated with mental fatigue during the use of the brain-computer interface [13]. Under different cognitive loads, Chen et al. adopted fMRI to measure the impact of mental fatigue on brain activation. ey evaluated the mental fatigue before and after each behavioral task using the visual simulation fatigue scale. Results suggested a close relationship between the allocation efficiency of neural resources and the aggravation of mental fatigue [14]. In summary, the mechanism of mental fatigue is complicated. Neuroimaging technology can monitor the human brain to some extent. At present, the theory of brain function network is introduced into the evaluation and analysis of mental fatigue; however, the nonlinear analysis of mental fatigue is rarely reported.
In this regard, to explore the data fusion in multimodal neuroimaging technology and seek a feasible method of evaluating human brain fatigue, the four-dimensional consistency of local neural activities (FOCA) and local multimodal serial analysis (LMSA) are first introduced to construct the EEG-fMRI multimodal neuroimaging data fusion system. en, the brain function network and fractal dimension are introduced based on the evaluation of the human brain fatigue state. e aims are to provide feasible directions for developing and applying neuroimaging technology and explore the relationship between fractal theory and brain function networks. e main contributions are as follows: (1) creatively, a multimodal neuroimaging data fusion system that integrates EEG, fMRI, and emiCCA is proposed, and its effectiveness in time-space matching is proved and (2) a method that can evaluate the relationship between human brain fatigue and brain function network is introduced based on the fractal dimension; this method can provide good sensitivity, pointing out a possible direction for human brain fatigue evaluation.

Temporal and Spatial Data Mining of Human Brain Based on FOCA under EEG-fMRI Fusion.
At present, the shared fusion of spatial data information mainly uses MRI data to provide information with higher spatial resolution, which offers very accurate spatial data information for EEG source positioning. Comprehensively, the major problem that still exists in the sharing and fusion of spatial information lies in the difference in spatial position between EEG and fMRI technologies [15]. From the perspective of temporal information sharing and fusion, since the EEG technology shows excellent performance in temporal resolution, the integration of data information in the time dimension should use EEG to provide fMRI with data information at the same time [16]. On the temporal level, the major limitation of the fusion between EEG and fMRI is the difference in their temporal resolutions. From the perspective of temporal-spatial information sharing and fusion, scholars are willing to put more emphasis on the integration of multimodal temporal-spatial information, in which the model-driven and nonmodel-driven are the two most frequently used data fusion methods [17][18][19]. e data collection of EEG and fMRI neuroimaging technologies is shown in Figure 1.
For fMRI imaging technology, to realize the mining of local temporal-spatial data information of the human brain nerves, the FOCA index is utilized. To obtain the algorithm of the FOCA index, the temporal correlation coefficient is calculated as follows: where r t ij corresponds to the Pearson correlation coefficient between the voxel i and time series j, and k corresponds to the corresponding number of voxels locally. For the m-th corresponding time point, the local spatial correlation coefficient of the corresponding adjacent time point is calculated as follows: where r corresponds to the Pearson correlation coefficient. For all time points, the corresponding average spatial correlation coefficient is calculated as follows: where N t characterizes the number of time points. On this basis, the expression and calculation for FOCA values are defined as follows: According to the above equation, the FOCA image of the entire human brain nerve is obtained through the numerical calculation of FOCA. Considering the differences between individuals, the FOCA image is defined as follows: Furthermore, in the simulation analysis of FOCA, the number of voxels is set to 25; the repetition time is set to 2 s; and the number of time points is set to 250. e design and implementation of the simulation experiment are shown in Figure 2. Figure 2 presents four different time-series characteristics: time consistency, space consistency, time-space consistency, and time-space inconsistency, which can reflect the local spatial activity state under four different situations. e entire simulation experiment is simulated and generated in a 5 * 5 grid. Specifically, for these four different situations, time consistency means that changes in activities based on time history are basically the same, while the state of space activities in the near-time state is inconsistent. Space consistency suggests that changes in activities in the time history are basically the same, while the state of space activities at the nearby time point is inconsistent. e other two cases can be deduced by analogy. Furthermore, to organically fuse EEG and fMRI information data and promote the effective acquisition of human brain function data, the index of LMSA is introduced, thus achieving the fusion analysis and characterization of local human brain data information. e fMRI data are expressed as follows: where M represents the corresponding number of time points, and N represents the corresponding number of voxels. For the activation value corresponding to the i-th voxel, the corresponding calculation is as follows: where i represents the i-th voxel, β i represents the regression coefficient of a single element, β cov represents the regression coefficient of the column vector, v i represents the typical correlation variable of the maximum correlation coefficient corresponding to EEG and fMRI, ] cov represents the covariate matrix including interfering signals such as linear drift, and ε represents the residual value. e calculation of the regression coefficient is as follows: where [.] + represents the inverse operation. Finally, by repeating the above calculations for all voxels, a regression Complexity 3 coefficient image of the entire brain is obtained. Correspondingly, the expression and calculation are as follows: where SE(·) represents the value of the standard deviation corresponding to β. rough the above-mentioned calculation and algorithm flow, the information data of EEG and fMRI are organically fused with the LMSA index. To test the LMSA method, the fMRI time series is set to 250; the repetition time is also set to 2 s; and the signal-to-noise ratio is set to 0.1. After 50 repeated calculations, the average result of the simulation analysis is obtained, thereby analyzing the fusion effect of EEG and fMRI information data.

Construction of the Multimodal Neuroimaging Data
Fusion System. For EEG and fMRI neuroimaging technologies, only a single spatial information registration cannot ensure that the components of EEG and fMRI are the same event. In addition to the difference between EEG and fMRI in the time dimension, the registration may fail [20,21]. Besides, in the process of data information fusion between EEG and fMRI, in addition to paying attention to the shared data information of the two modalities, at the same time, the uncertainty of shared data information should be minimized. From the perspective of data information sharing, the data fusion between EEG and fMRI indicates the same active time course in the same spatial position. us, time and space registrations are necessary. On this basis, according to the multimodal data fusion method, a data fusion system that can distinguish the difference between time and space is built. In this system, different time and space data fusion methods are adopted for the registration between modalities.
At the same time, the system also includes multiple layers of credibility from time-space misregistration to time-space registration.
e realization of the shared multimodal neuroimaging data fusion system is shown in Figure 3.
To realize the effective analysis of the data fusion system of data EGG and fMRI neuroimaging, the unsupervised learning method is utilized, and the index of eigenspace maximal information canonical correlation analysis (emiCCA) is introduced, which evaluated both the linear and nonlinear correlations among the data. e realization of this analysis index is based on the replacement of correlation coefficient by maximal information coefficient (MIC). First, the corresponding expression and calculation of the MIC coefficient are defined as follows: where X i and Y j represent the frequency distribution of X i − Y j falling in a grid, I * (·; ·) represents the maximum mutual information corresponding to the grid division at a certain resolution, and |X i ||Y j | < B characterizes that the resolution of the corresponding grid is smaller than the B value. Furthermore, through the above equation, the MIC matrix is obtained, and its corresponding expression and calculation are as follows: If the weight vectors α and β meet the following conditions  where α and β correspond to the weight vectors of feature spaces X and Y. With the help of α and β, each variable in the corresponding data set is quantified to show the correlations among the data sets. e square root of the positive number corresponding to the eigenvalue in Equation (12) above is actually emiCCA. While emiCCA is tested, the number of data points is set to 1600 and the data dimensions are set to (3,2), (6,4), (12,8), (18,12), (24,16), and (30, 20). To explore the impact of the number of data points and noise, the corresponding functional correlations among variables are, respectively, linear function (F1), quadratic function (F2), absolute value function (F3), cosine function (F4), exponential function (F5), circular equation (F6), inseparable function (F7), equation (F8), and independent random variable (F9). Besides, in the case of noise, the emiCCA method under different function variables as well as the linear CCA (lCCA) method and the kernel CCA (kCCA) method are compared and investigated. e implementation of this system has gone through four stages, i.e., weight extraction, time registration, space registration, and time-space registration. First, in the weight extraction stage, the independent component analysis (ICA) method is used [22,23]. Besides, the temporal and spatial ICA is used to decompose the EEG and fMRI information data. e corresponding expressions and calculations are as follows: where Y e represents the EEG-related data at the trial level, n 1 represents the conductive electrode, m 1 represents the corresponding time point, Y f represents the relevant data after fMRI preprocessing, B e represents the EEG space map after decomposition, B f represents the spatially independent components, and ε corresponds to the residual. Furthermore, the amplitude of EEG-related events is expressed and calculated by the following equation: where t ′ represents the time point corresponding to the maximum amplitude. e single amplitude calculation of fMRI is achieved in two steps. One is the calculation of the hemodynamic response function (HMRI) of the fMRI time series, which is defined as follows: where M + represents the generalized inverse corresponding to the convolution matrix, and T f represents the time series. e second is the calculation of the horizontal amplitude of a single trial of the corresponding time series of fMRI, which is defined as follows: where D represents the design matrix corresponding to the start time of a single trial, ⊗ represents the convolution operation, Z f represents the amplitude of time-series-related events, and ε corresponds to residuals. rough the above calculations and corresponding definitions, the amplitude sequence corresponding to EEG and fMRI is finally obtained, which indicates the related dynamic changes of EEG and fMRI. According to different  repetition times, the hemodynamic response functions (HRFs) are divided and compared with HRF-1, HRF-2, HRF-3, and HRF-4, and their corresponding repetition times are 0, 1.5, 3, and 4, respectively.
In the temporal registration stage, the MIC is used to complete the time registration between EEG and fMRI. e corresponding calculation is as follows: where Z 1 and Z 2 correspond to the frequency distribution that falls in a grid, I * (·; ·) represents the maximum mutual information under a certain grid, and |z 1 ||z 2 | < G represents that the resolution ratio of the grid is smaller than G.
In the spatial registration stage, for the location analysis of the EEG source, the parameter empirical Bayes model is used, and the corresponding expression and calculation are as follows: where B (i) e represents the i-th EEG topographic map, L e represents the transfer matrix of the known head model, Φ (i) e represents the source distribution corresponding to the unknown dipole, and E 1e and E 2e correspond to the random terms between the electrode and the source spatial level. Furthermore, the expression and calculation of the prior information of covariance are as follows: where c represents a hyperparameter and has a nonnegative value, V represents a covariance basis matrix, B f represents a spatially independent component corresponding to fMRI, and MSP represents a sparse source. In summary, in the constructed multimodal neuroimaging data fusion system, temporal registration is achieved through MIC coefficients, and spatial registration is achieved through spatial prior information. Each area in the system is divided into five component sources, which are recorded as visual area (S1), default network (S2), auditory cortex (S3), left-hand cognition (S4), and right-hand cognition (S5). e simulation data set used is randomly generated through standard uniform distribution to analyze the performance of emiCCA, lCCA, and kCCA. e number of data points used for analysis is set to 1200; the dimension of data set X is set to 6, and the dimension of data set Y is set to 4. On this basis, different data dimensions are set to test the influence of data dimensions on emiCCA, lCCA, and kCCA.

Fractal Dimension and Calculation Improvement of
Complex Networks. Fractals originally represented phenomena or processes with self-similar characteristics, whose original indications were irregularities and fractions. ere is no definite meaning for fractal at present. However, despite the definitions, self-similarity, scale-freeness, and selfaffinity are the foremost characteristics of a fractal. Fractals exist extensively in nature and society; thus, they can be divided into four types: natural fractal, time fractal, social fractal, and thinking fractal.
Dimension is a fundamental concept in geometry. However, it is difficult to describe natural objects such as mountains using conventional geometric features. e fractal dimension can quantitatively describe the basic composition parameters, which analyzes the irregularity and complexity of the object.
ere is a positive correlation between the size of the fractal dimension and the complexity of the described object. e fractal features of a complex network represent the self-similarity of the network structure, which can measure the degrees of irregularity and complexity of the network. Complex networks include social relationship networks and cellular networks. Research on the fractal features of complex networks mainly adopts the geometric method based on the box covering and the algebraic method based on spectral analysis, in which the box covering method can be described as follows: where n b represents the number of boxes that can cover the entire network, l b represents the size of the box, and d b represents the dimension of the box in the complex network. However, when calculating the fractal dimension d b using the above equation, finding the smallest number of boxes is one of the difficulties. In this regard, a greedy coloring algorithm is proposed by improving the box covering method. e difference is that each box in the greedy coloring algorithm does not need a central node, and all the nodes in a box present a random arrangement. According to the box covering method, if the size of the box given for a network N is l b � 3, the shortest path in the network will be connected, that is, nodes with a distance of three are connected to obtain network N 1 .
en the newly obtained network is colored to make the nodes that are connected to each other have different colors, and a new network N 2 can also be obtained from this. After the coloring operation is completed, the new network N 3 can be obtained once the initial connection is restored. e number of color types corresponding to the new network is the number of boxes n b required to determine the box size in the overall network. To calculate the fractal dimension in the complex network, first, all the nodes are randomly numbered. For the determined box size l b , the color corresponding to the first node is assigned a value of 0, and the box size is set to l b � 1. en the distance between the current node i and the remaining node j is calculated. If all nodes satisfy l ij ≥ l b , one of the nodes is selected as the unused color under the current box size l b , which is regarded as the color value c ilb corresponding to the node i. e above steps are repeated until l b � l max b is satisfied. e number of color values used in each column is calculated, and the value obtained is the number of boxes n b needed to cover the overall network under different box sizes. Finally, log(l b ) and log(n b ) are fitted, and the obtained 6 Complexity absolute value of the slope is the fractal dimension d b corresponding to the complex network.

Mental Fatigue Detection and Evaluation Based on emiCCA Nonlinear
Index. When constructing the above multimodal neuroimaging data fusion system, nonlinear correlations are considered for the first time based on the index of emiCCA. e human brain is actually a complex nonlinear system; thus, the nonlinear analysis method is accurate in analyzing human brain activities, which is also effective for investigating the characteristics of the human brain. Mental fatigue caused by work performance decline and impaired cognitive level is seriously affecting people's living conditions. erefore, it is necessary to monitor mental fatigue effectively. In response to this problem, the formation of mental fatigue is analyzed based on the fractal features of the complex network by constructing a brain function network.
Complex networks can be divided into directed and undirected networks or binary and weighted networks where the latter characterizes the network with a weight of 1. Methods to construct the brain function network include valuing a weight and valuing a fixed network's edge number, written as M1 and M2, respectively. M1 can reveal the effect of weight on the network structure. For an adjacency matrix, when the weight as a whole is at a high level, the number of edges corresponding to the brain function network is also large, which can distinguish the network features such as clustering coefficient and global efficiency. M2 emphasizes the influence of the network edges' spatial distribution on the network features, which can effectively distinguish the differences in the features of the brain function network. Here, a series of thresholds are taken from M1 and M2 to analyze the effect of network feature composition on mental fatigue more precisely. e determination of the threshold aims to ensure that no isolated nodes are in the constructed brain function network so that the difference in the network feature composition can be expanded at different time stages. e greedy coloring algorithm optimized above is used to analyze the fractal characteristics of the brain function network in the process of mental fatigue, and the calculation threshold is set to 0.36. e fractal dimensions of the binary brain function network and the weighted brain function network are analyzed at six different time nodes (t 0 , t 1 , t 2 , t 3 , t 4 , and t 5 ), where t 0 represents the initial stage, t 1 to t 5 mean that the human brain is in a state of fatigue, and the degree gradually deepens.

Results of FOCA Simulation Analysis.
rough the calculation of the temporal correlation coefficient, spatial correlation coefficient, and FOCA value, the simulation analysis results of the FOCA index are shown in Figure 4.
In Figure 4, A to D and A′ to D′ represent the mean value and the standard deviation, respectively, corresponding to the FOCA index when the time is consistent, the space is consistent, the time space is inconsistent, and the time space is consistent.
As shown in Figure 4, the statistical value corresponding to the FOCA index ranges between the values of the time correlation coefficient (Ct) and the space correlation coefficient (Cs) despite time consistency, space consistency, time-space consistency, or time-space inconsistency.
erefore, under the premise of time-space consistency, Ct, Cs, and FOCA values are the closest. e simulation results in the case of time-space consistency are very stable. rough data analysis, it is found that the FOCA index is well-performed on the temporal and spatial consistencies during the process of local voxel activities.
us, it is speculated that if this index is used in fMRI neuroimaging technology, it will show and characterize the temporalspatial consistency characteristics of local regions.
In the indication and representation of the consistency of the characteristics of spontaneous activity related to the local region of the human brain nerve, methods and indexes including local consistency, integrated local correlation, and local functional connection density have been used. However, these traditional indexes still have limitations, such as that the local consistency index method is dependent on voxel size [24]. Pu et al. analyzed the abnormal synchronization of fMRI signals in patients based on FOCA indexes. ey found that the overall functional connectivity strength and density of the areas with significant differences in FOCA were different, pointing out directions for the pathophysiological mechanism of patients with abnormal brain function [25]. ese findings can support the present work. e FOCA index used fully considers the temporal correlation between voxels in local regions and the spatial correlation between voxels in local regions at adjacent time points. e above analysis results show that if this index method is applied to fMRI neuroimaging technology, it will play an important role in the mining of time-space information of the spontaneous activity process in the local region of the human brain nerves.

EEG-fMRI Shared Multimodal Simulation Analysis.
rough consideration of different HRF functions, the simulation analysis results for the LMSA method and GLM method under different signal-to-noise ratios are shown in Figure 5.
As shown in Figure 5, the regression coefficients of the both LMSA method and GLM method are positively related to the changes in the signal-to-noise ratios. However, in general, the effect of LMSA is better than that of GLM, and the significance level p is <0.05. From the perspective of the HRF function, given the differences in signal-to-noise ratio, the regression coefficient obtained by the LMSA method is much larger than the regression coefficient obtained by GLM method. When the HRF function corresponds to HRF-3, the corresponding activation is detected under the different signal-to-noise ratios by the LMSA method; in contrast, it cannot be detected by the GLM method.
Based on the data fusion analysis of EEG and fMRI, the proposed LMSA method fully considers the shared timerelated data information between multimodalities and also takes into account the uncertainties in multimodal neuroimaging data fusion. e above simulation analysis results show that the introduction of this method has an important role in solving the problem of low signal-to-noise ratio in the HRF. erefore, it is expected to solve problems such as human brain nerve function disorders. To promote the maintenance of the healthy state of the human brain nervous system, the proposed method also laid a foundation for the fusion of multimodal data of neuroimaging technologies such as EEG and fMRI. Wu et al. analyzed the relationship between fMRI neuroimaging technology and HRF indicators regarding brain activity in the resting state. ey found that combining fMRI and HRF could effectively track the neurovascular coupling [26]. Obviously, this effect becomes more significant under EEG-fMRI fusion.

Implementation of Multimodal Neuroimaging Data Fusion System.
Given different function variables, the changes in corresponding coefficients of the three methods, such as emiCCA, lCCA, and kCCA, are shown in Figure 6. Given different data dimensions and different data points, the timeconsuming changes produced by these three methods are shown in Figures 7(a) and 7(b).
According to Figures 6 and 7, despite the linear or nonlinear relationships, the coefficient corresponding to emiCCA is the most significant; however, that corresponding to the independent random variable is not significant. In contrast, lCCA can obtain significant correlation coefficients for quadratic functions and exponential functions, while kCCA provides a corresponding word number of 1 basically for any function. According to the time consumption changes in these three methods, in different data dimensions, the average time consumption corresponding to emiCCA is distributed between those of lCCA and kCCA, showing the same trend under different data points. e correlation coefficient and average time consumption results reveal that the emiCCA method has obvious advantages.
rough the temporal registration based on MIC coefficient and the spatial registration based on spatial prior information, the simulation analysis results of EEG temporal registration accuracy and fMRI spatial registration accuracy are obtained, as shown in Figure 8.
rough data analysis, it is found that the components of the temporal-spatial registration show better results in terms of time accuracy based on EEG and spatial accuracy based on fMRI. In contrast, the components in the second level of the Based on the problem of registration failures in EEG and fMRI, a multimodal neuroimaging data fusion system is constructed, and a hierarchical data information structure for temporal-spatial registration is proposed. As shown in the simulation analysis results, the construction of the data fusion system makes the data information shared by EEG and fMRI more prominent; at the same time, this system significantly reduces the uncertainty between the corresponding modalities. Jonmohamadi et al. introduced the source space into the fusion of EEG and fMRI neuroimaging technology, revealing its effectiveness in temporal and spatial data matching [27]. A credible result of level matching can be obtained in the present work based on the fusion method in the first level. Specifically, it can be explained as that the first level of temporal and spatial matching corresponding to EEG and fMRI aims to reveal the most credible component of brain behavior. Unlike the first level, the main function of the second level is to provide supplementary explanatory information.

Mental Fatigue Evaluation Based on Binary Network
Fractal Dimension Analysis. When the calculated threshold is 0.36, the fractal dimension analysis results of the binary brain function network corresponding to different time stages are presented in Figure 9.
In the six different time stages, log(l b ) and log(n b ) show better fitting results; moreover, when the degree of mental fatigue increases, the fractal dimension corresponding to the brain function network increases. According to Equation (20), thresholds selected for M1 are 0.15, 0.2, and 0.3, and those for M2 are 40, 65, and 90, respectively. e corresponding results are the average values obtained after 100 calculations. e calculation results of the fractal dimension in the binary network obtained corresponding to M1 and M2 are displayed in Figures 10(a) and 10(b).
When the threshold value is 0.32, the fractal dimension corresponding to M1 shows a significant change, presenting a correspondence relationship with the results in Figure 9.
e fractal dimension of all selection thresholds corresponding to M2 has no significant changes in different time stages. Specifically, when the number of network edges is large, the fractal dimension of the corresponding brain function network is about 2.2; when the number of network edges is small, the fractal dimension of the corresponding brain function network is about 1.6. By aiming to evaluate  the brain fatigue state, Li et al. analyzed the influence of mental fatigue on the fractal dimension of the brain function network. ey found that the increase in mental fatigue was positively correlated with the fractal dimension, while the fractal dimension of the weighted network was more sensitive to mental fatigue [28]. ese results can support the research results in the present work. e difference is that the emiCCA index is introduced in the present work.

Mental Fatigue Evaluation Based on Weighted Network
Fractal Dimension Analysis. When the calculated threshold is 0.36, the fractal dimension analysis results of the weighted brain function network corresponding to different time stages are presented in Figure 11.
As shown in Figure 11, log(l b ) and log(n b ) corresponding to different time stages provide good fitting results. Even if the brain is in a fatigued state, the weighted brain function network can maintain the fractal structure, and the increase in the degree of mental fatigue also shows a positive correlation with the fractal dimension, which is similar to the binary brain function network. In contrast, in the time stages t 3 and t 4 , the fractal dimension in the binary brain function network cannot be distinguished, while in the weighted brain function network, the distinction is noticeable. us, the latter can provide better performance in this regard. Under the same threshold setting, the calculation results of the fractal dimension corresponding to M1 and M2 are shown in Figures 12(a) and 12(b). e increase in mental fatigue degree is positively correlated to the fractal dimension under both M1 and M2. With the further deterioration of fatigue degree, the fractal dimension corresponding to the weighted brain function network increases. In contrast, M2's description of fractal dimension is better than M1, and the changing trend under different time stages also shows good consistency. e above fractal dimension analysis results based on the binary brain function network and the weighted brain function network are summarized. M1 has a better response to mental fatigue in the binary brain function network because of the number of edges in the network. In the weighted brain function network, M2 shows better consistency for mental fatigue because the network weight has a greater effect on the fractal dimension at this time. Briefly, the weighted brain function network is more sensitive to the degree of mental fatigue. is result can also be caused by the more comprehensive coverage of the box size by the weighted brain function network. e fractal dimension can also measure the degree of complexity for self-similar structures.
e above analysis suggests that the mental Complexity fatigue state will make the brain function network more complicated, and the increase in this complexity can aggravate the degree of mental fatigue.

Conclusion
e research objects are EEG and fMRI neuroimaging technologies. Two dimensions of space and time are introduced. e FOCA based on fMRI optimizes the algorithm indexes. Based on the LMSA index under data fusion, a multilayer and multimodal neuroimaging data fusion system is constructed innovatively. Furthermore, by introducing the idea of fractal dimension, a novel method that can evaluate brain function network is proposed. rough simulation, the introduction of FOCA and LMSA indexes shows a good effect in temporal and spatial voxel activities under the EEG-fMRI fusion, which can well reflect the characteristics of time-space consistency in local areas. e LMSA index comprehensively considers multimodal shared time data and neuroimaging data fusion, making it possible to deal with human brain neurological disorders. e organic fusion of time accuracy based on EEG and spatial accuracy based on fMRI provides effective ideas for dealing with brain function problems. Regarding the responses to human brain fatigue, the weighted brain function network provides excellent performance, and the increase in fractal dimension also reflects the complexity of the brain function network. e research results can provide a direction for developing shared multimodal neuroimaging technology. However, the internal mechanism of FOCA has not yet been involved in the present work; the focus is on the construction of the data fusion system and the combination with the classification theory; nevertheless, the specific practical application has not yet been involved. A more in-depth analysis will be provided for each index, and a more detailed analysis will be performed to evaluate human brain fatigue in future works.

Data Availability
All data are fully available without restriction.

Conflicts of Interest
e authors declare that they have no conflicts of interest.