A Successful Treatment Regimen for the Prevention of Sinusitis after Maxillary Sinus Floor Elevation Surgery in a High-Risk Case

Maxillary sinus floor elevation (sinus lift) is a widely recognized dental-surgical approach for dental implant placement. However, for an otorhinolaryngological high-risk patient with severe anatomic-structural impairments of the maxillary sinus drainage pathway, surgical intervention is recommended before sinus lift to avoid postsinus lift maxillary sinusitis. Here, we show a case that postsinus lift maxillary sinusitis in such a high-risk patient was noninvasively prevented by the collaboration of otorhinolaryngologist and dentist. A 48-year-old Japanese male intended to undergo a sinus lift for dental implant placement by periodontist. Otorhinolaryngologist found septal deviation, concha bullosa, the presence of Haller cell, and nasal mucosal swelling by the nasal allergy, while no sinusitis and diagnosed him as a “high-risk case” for postsinus lift maxillary sinusitis. The patient was administered preoperative topical steroid and leukotriene receptor antagonist in addition to perioperative antibiotic prophylaxis so that his complication was noninvasively prevented. Thus, this case suggested that consultation from dentist to otorhinolaryngologist provides benefit to the patients who have been diagnosed as “high-risk case” for postsinus lift maxillary sinusitis.


Introduction
Maxillary sinus floor elevation (sinus lift) introduced by Boyne and James [1] is a widely recognized dental surgery to create a mucoperiosteal pocket over the maxillary floor and beneath the Schneider's membrane in which to place the bone graft material or dental implant to rehabilitate the upper dental arch, in the atrophic maxilla. Although sinus lift is an effective approach, maxillary sinusitis sometimes occurs as a complication after surgery [2,3]. Anatomic-structural impairments of the maxillary sinus drainage pathway such as septal deviation, concha bullosa, the presence of Haller cell, and nasal mucosal swelling owing to nasal allergy increase in the incidence of maxillary sinusitis after sinus lift [4]. us, these patients are diagnosed as a "reversible contraindication case" or "high-risk case" in the field of otorhinolaryngology for the sinus lift [5,6]. For the patient with severe anatomicstructural impairments of the maxillary sinus drainage pathway, surgical intervention is recommended before sinus lift to avoid postsinus lift maxillary sinusitis.
If patients do not agree with the surgical treatment, "noninvasive treatment" with reducing maxillary sinusitis incidence safely should provide great benefit. Here, we report a successful treatment modality for the noninvasive prevention of sinusitis after the sinus lift in an otorhinolaryngological high-risk case.

Case Report
A 48-year-old Japanese male came to otorhinolaryngology in our hospital. Although periodontist (S-Y, M) planned bilateral sinus lift and implant placement to him, he has complained of alternating nasal congestion for one year. us, he consulted an otorhinolaryngologist (BY). ere was no history of any operation in the head and neck, and he had a nasal allergy. Preoperative computer tomography (CT) and nasal endoscopic examination indicated septal deviation, concha bullosa, the presence of Haller cell, nasal mucosal swelling owing to nasal allergy, and maxillary sinus accessory ostium, while no sinusitis was detected ( Figure 1). erefore, the patient was judged as a reversible otorhinolaryngological contraindication to a sinus lift (a high-risk case). After we explained whether he received presinus lift medical conservative therapy or presinus lift surgical treatment such as functional endoscopic sinus surgery (FESS) in order to prevent maxillary sinusitis after sinus lift, he chose medical conservative therapy. us, we preoperatively prescribed both topical nasal steroid (fluticasone propionate aqueous nasal spray) and leukotriene receptor antagonist (pranlukast hydrate) for him. Two months later, nasal congestion almost disappeared, and he underwent bilateral maxillary sinus floor elevation with bone graft material (Cytrans Granules ® , GC company, Tokyo, Japan) by using sinus lift technique.
After surgery, no clinical symptoms had occurred. No maxillary sinusitis was found in follow-up panoramic radiography at 2 months after bilateral sinus lifts (Figure 2), and the postoperative course was uneventful before his 7 months follow-up evaluation. He will undergo bilateral implant placement in other local dental clinics.

Discussion
Pignatro et al. proposed that otorhinolaryngological contraindications to a sinus lift can be divided into those presumably irreversible and those that are potentially reversible [5,6]. e contraindications were categorized into irreversible and reversible ones. Irreversible contraindications involve Wegener's   [7]. Because the patient did not like more than one surgery, he selected medical conservative therapy. Medical conservative therapy for the prevention of maxillary sinusitis after sinus lift includes perioperative antibiotic prophylaxis and preoperative administration of topical steroid [6]. Lee et al. mentioned that the use of nasal decongestants should be considered to reduce the risk of postoperative sinusitis [4]. However, we did not use vasoconstrictor because the use of it might further compromise the already low oxygen tension in the sinus [8]. Instead of vasoconstrictor, we prescribed a leukotriene receptor antagonist for him because he had nasal mucosal swelling owing to nasal allergy. Consequently, the complications such as maxillary sinusitis did not occur after sinus lift.
In summary, we reported a successful treatment regimen to prevent sinusitis after maxillary sinus floor elevation in a high-risk case. Administration of preoperative topical steroid and leukotriene receptor antagonist in addition to perioperative antibiotic prophylaxis (Sawacillin ® ) may be effective for the prevention of sinusitis after sinus lift as medical conservative therapy to high-risk cases who had both anatomic-structural impairments of the maxillary sinus drainage pathways and nasal allergy although there is certain limitation.
erefore, further clinical trial is required to insist on our "noninvasive" treatment regimen, which is a great advantage for the patient, to regulate the inflammatory reaction of nasal mucosa in such high-risk cases. Furthermore, this case suggested that close cooperation between otorhinolaryngologist and dentist provides benefit to the patients diagnosed as "high-risk case" for a sinus lift.

Data Availability
e data used to support the findings of this study are available from the corresponding author upon request.

Consent
Written consent was obtained from the patient for submission of this paper.

Conflicts of Interest
e authors declare that there are no conflicts of interest.